61563-39-1

Usage

Uses

Used in Medicinal Chemistry:
2-acetyl-1,2,3,4-tetrahydroisoquinoline-7-sulfonyl chloride is used as a key intermediate in the synthesis of pharmaceutical compounds for [application reason]. Its reactivity allows for the creation of diverse drug candidates with potential therapeutic properties.
Used in Drug Development:
In the pharmaceutical industry, 2-acetyl-1,2,3,4-tetrahydroisoquinoline-7-sulfonyl chloride is used as a building block for the development of new drugs, leveraging its ability to form a wide range of chemical bonds with various molecular entities.
Used in Organic Synthesis:
2-acetyl-1,2,3,4-tetrahydroisoquinoline-7-sulfonyl chloride is utilized as a versatile reagent in organic synthesis for [application reason], such as the formation of complex organic molecules and the creation of novel chemical entities with potential applications in various fields.

Upstream product

• 91-21-4 1,2,3,4-tetrahydroisoquinoline 
• 14028-67-2 N-acetyl-1,2,3,4-tetrahydroisoquinoline 

Downstream Products

• 74291-47-7 2-Acetyl-1,2,3,4-tetrahydro-isoquinoline-7-sulfonic acid (4-trifluoromethyl-phenyl)-amide 
• 74291-45-5 2-Acetyl-1,2,3,4-tetrahydro-isoquinoline-7-sulfonic acid (3-trifluoromethyl-phenyl)-amide 
• 74291-46-6 2-Acetyl-1,2,3,4-tetrahydro-isoquinoline-7-sulfonic acid (3,4-dimethyl-phenyl)-amide 
• 74291-50-2 2-acetyl-7-(3-chlorobenzeneaminosulfonyl)-1,2,3,4-tetrahydroisoquinoline 
• 74291-48-8 2-Acetyl-1,2,3,4-tetrahydro-isoquinoline-7-sulfonic acid (4-chloro-3-trifluoromethyl-phenyl)-amide 
• 31404-61-2 1,2,3,4-tetrahydroisoquinoline-7-sulfonamide 
• 74291-29-5 1,2,3,4-Tetrahydro-isoquinoline-7-sulfonic acid (4-chloro-3-trifluoromethyl-phenyl)-amide; hydrochloride 
• 74291-36-4 1,2,3,4-Tetrahydro-isoquinoline-7-sulfonic acid [2-(4-chloro-phenyl)-ethyl]-amide; hydrochloride 
• 74291-26-2 1,2,3,4-Tetrahydro-isoquinoline-7-sulfonic acid (3-trifluoromethyl-phenyl)-amide; hydrochloride 
• 74291-28-4 1,2,3,4-Tetrahydro-isoquinoline-7-sulfonic acid (4-trifluoromethyl-phenyl)-amide; hydrochloride 
• 74291-32-0 4-(1,2,3,4-Tetrahydro-isoquinoline-7-sulfonylamino)-benzoic acid; hydrochloride 
• 74291-24-0 1,2,3,4-Tetrahydro-isoquinoline-7-sulfonic acid (3,4-dichloro-phenyl)-amide; hydrochloride 
• 74291-38-6 1-(4-Chloro-phenyl)-2-(1,2,3,4-tetrahydro-isoquinoline-7-sulfonyl)-ethanone; hydrochloride 
• 74291-34-2 7-N-(p-chlorophenyl)-7-N-methyl-1,2,3,4-tetrahydroisoquinoline-7-sulfonamide hydrochloride 

Relevant academic research and scientific papers

Compounds with cardiac myosin activating function and pharmaceutical composition containing the same for treating or preventing heart failure

The present invention relates to a compound having a cardiotonic activating function and a pharmaceutical composition containing the same. The composition comprising the compound according to the present invention is effective in preventing or treating heart failure. In addition, the compound is represented by chemical formula 2 or is pharmaceutically acceptable salt thereof.COPYRIGHT KIPO 2016

Compounds with cardiac myosin activating function and pharmaceutical composition containing the same for treating or preventing heart failure

Disclosed are a compound having cardiotonic activity and a pharmaceutical composition containing the same, and the composition containing the compound, according to the present invention, is useful for preventing and treating heart failure.COPYRIGHT KIPO 2016

Antiallergic imidosulfamides

Imidosulfamide derivatives useful in the treatment of allergic conditions are prepared by reaction of an appropriately substituted tetrahydroisoquinoline and chlorosulfonylisocyanate in the presence of a non-nucleophilic organic base. Pharmaceutical compo

N,N'-Bis[substituted-1,2,3,4-tetrahydroisoquinolinolyl]disulfonylimides and antiallergic compositions and method of use

Imidodisulfamide derivatives useful in the treatment of allergic conditions are prepared by reaction of an appropriately substituted tetrahydroisoquinoline and bis(chlorosulfonyl)imide in the presence of a tertiary amine.

7- and/or 8-Sulfur substituted 1,2,3,4-tetrahydroisoquinoline compounds

1,2,3,4-Tetrahydroisoquinoline compounds having 7- and/or 8-sulfur substituents are inhibitors of phenylethanolamine N-methyltransferase.