61568-51-2

Usage

Uses

Used in Pharmaceutical Industry:
4-BROMOBENZALDEHYDE PROPYLIDENE ACETAL is used as a key intermediate for the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential therapeutic benefits.
Used in Agrochemical Industry:
In the agrochemical sector, 4-BROMOBENZALDEHYDE PROPYLIDENE ACETAL is utilized as a precursor in the production of agrochemicals. Its involvement in the synthesis process contributes to the creation of effective crop protection agents.
Used in Fine Chemicals Production:
4-BROMOBENZALDEHYDE PROPYLIDENE ACETAL is employed as an intermediate in the manufacture of other fine chemicals. Its versatility as a building block facilitates the production of a wide range of specialty chemicals for various applications.
Used as a Reagent in Chemical Reactions:
4-BROMOBENZALDEHYDE PROPYLIDENE ACETAL is used as a reagent in various chemical reactions, such as condensation and acetal formation. Its reactivity enables the synthesis of complex organic molecules for research and industrial purposes.
Used in Flavor and Fragrance Industry:
4-BROMOBENZALDEHYDE PROPYLIDENE ACETAL has applications in the flavor and fragrance industry, where it is used in the synthesis of aroma chemicals. Its ability to contribute to the creation of unique scents and flavors makes it a valuable component in this sector.

Upstream product

• 1122-91-4 4-bromo-benzaldehyde 
• 504-63-2 trimethyleneglycol 
• 17887-80-8 1,3-bis(trimethylsiloxy)propane 
• 24856-58-4 1,1-dimethoxy-1-(4-bromophenyl)methane 
• 149-73-5 trimethyl orthoformate 

Downstream Products

• 140834-22-6 1,8-Bis<4-(1,3-dioxan-2-yl)phenyl>anthracen 
• 87199-17-5 4-formylphenylboronic acid, 
• 27913-99-1 4-(4-methylpiperazin-1-yl) benzaldehyde 
• 128376-65-8 5,5-dimethyl-2-(4-formylphenyl)-1,3,2-dioxaborinane 
• 163164-11-2 (E)-7-[4-(4-Formyl-benzyloxy)-phenyl]-7-pyridin-3-yl-hept-6-enoic acid 
• 163164-10-1 (E)-7-[4-(4-Formyl-benzyloxy)-phenyl]-7-pyridin-3-yl-hept-6-enoic acid ethyl ester 
• 140834-23-7 4,4'-(anthracene-1,8-diyl)dibenzaldehyde 
• 140834-33-9 (E,Z)-1,8-Bis<4-<2-(3,5-di-tert-butylphenyl)ethenyl>phenyl>anthracen 
• 140834-24-8 (E,E)-1,8-Bis<4-<2-(3,5-di-tert-butylphenyl)ethenyl>phenyl>anthracen 

Relevant academic research and scientific papers

"Post-it" type connected DNA created with a reversible covalent cross-link

We report the development of a new heterobase that is held together through reversible bonding. The so-formed cross-link adds strong stabilization to the DNA duplex. Despite this, the cross-link opens and closes through reversible imine bonding. Moreover,

A supramolecular photocatalyst composed of a polyoxometalate and a photosensitizing water-soluble porphyrin diacid for the oxidation of organic substrates in water

A diprotonated form of a cationic water-soluble saddle-distorted porphyrin (H416+) forms stable supramolecular assemblies with multianionic polyoxometalates (POMs) by electrostatic interactions. An assembly of H416+ with a Ru-substituted POM can perform photocatalytic oxidation of organic substrates in water under visible-light irradiation through adduct formation of the H416+ moiety with an oxidant.

PD-1/PD-L1 INHIBITORS

Compounds according to formula (I), methods of using said compounds singly or in combination with additional agents and compositions of said compounds for the treatment of cancer are disclosed.

Visible-light-induced acetalization of aldehydes with alcohols

In this work, we have achieved a simple and general method for acetalization of aldehydes by means of a photochemical reaction under low-energy visible light irradiation. A broad range of aromatic, heteroaromatic, and aliphatic aldehydes have been protected under neutral conditions in good to excellent yields using a catalytic amount of Eosin Y as the photocatalyst. Our visible light mediated acetalization strategies are successful for more challenging acid-sensitive aldehydes and sterically hindered aldehydes. Notably, this protocol is chemoselective to aldehydes, while ketones remain intact.

Syn-selective kobayashi aldol reaction using acetals

The Kobayashi aldol reaction has been used to construct anti-aldol products by remote stereoinduction. Since the product of the Kobayashi aldol reaction has a typical polyketide structure, this reaction has been applied to the total synthesis of natural p

Mesoporous poly-melamine-formaldehyde (mPMF)-a highly efficient catalyst for chemoselective acetalization of aldehydes

A mesoporous poly-melamine-formaldehyde polymer with a high surface area, good porosity and a high density of amine and triazine functional groups was investigated as a highly efficient hydrogen-bonding catalyst. This porous organic polymer was found to be highly effective in catalyzing chemoselective acetalization of aldehydes, without the consumption of any dehydrating agents. The turnover frequency of mesoporous poly-melamine-formaldehyde is hundreds of times higher than melamine monomer, and this high efficiency is due to the high density of aminal (-NH-CH2-NH-) groups and triazine rings in the polymer network, which provides an inherently powerful system with multiple hydrogen bonds. This unique characteristic imparts mesoporous poly-melamine-formaldehyde polymer with a very high activity as a heterogeneous organocatalyst. The polymer is also low cost, and easy to be synthesized and recycled.

A METHOD OF ACETALIZING AN ALDEHYDE

A method of acetalizing an aldehyde comprising reacting said aldehyde with an alcohol in the presence of a polymeric catalyst to form an acetal wherein the polymeric catalyst is a mesoporous poly-melamine-formaldehyde polymer.

Indium(III) triflate catalysed transacetalisation reactions of diols and triols under solvent-free conditions

Acyclic acetals and ketals undergo transacetalisation in the presence of catalytic quantities of indium(III) triflate (In(OTf)3) and diols or triols under solvent-free conditions to generate the corresponding cyclic acetals and ketals in excellent yield. The methodology has been further developed to encompass a tandem acetalisation-acetal exchange protocol, which provides a facile and high yielding route to cyclic ketals from unreactive ketones under very mild reaction conditions.

Indium triflate mediated tandem acetalisation-acetal exchange reactions under solvent-free conditions

Acyclic acetals and ketals undergo exchange reactions in the presence of catalytic quantities of indium(III) triflate and diols to generate the corresponding cyclic acetals and ketals in excellent yield. The protocol is rapid, employs mild conditions and can be adapted to employ solvent-free reaction conditions. We have further developed this methodology to encompass a tandem acetalisation-acetal exchange protocol which provides facile access to cyclic ketals from unreactive ketones also under very mild, solvent-free reaction conditions.

Acetalization of carbonyl compounds catalyzed by bismuth triflate under solvent-free conditions

Carbonyl compounds were converted to the corresponding 1,3-dioxolanes and 1,3-dioxanes with ethylene glycol and 1,3-propandiol in the presence of bismuth triflate under solvent-free conditions. In addition, high chemoselective protection of aldehydes in the presence of ketones has been achieved.