61589-68-2

Upstream product

• 638-29-9 n-valeryl chloride 
• 7782-50-5 chlorine 
• 71-43-2 benzene 

Downstream Products

• 99419-67-7 4-chloro-heptan-3-one 
• 162375-42-0 N-4'-methylphenyl-2-(phenylthio)pentanamide 
• 220801-75-2 2-chloro-pentanoic acid 4-formyl-phenyl ester 
• 861844-38-4 6-ethyl-6-(3-methoxy-phenyl)-4-methyl-2-propyl-morpholin-3-one 
• 861844-39-5 6-ethyl-6-(3-methoxy-phenyl)-4-methyl-2-propyl-morpholin-3-one 
• 114351-30-3 2-Chloro-pentanoic acid {2-[2-(thiazol-2-ylcarbamoyl)-acetyl]-6-trifluoromethyl-phenyl}-amide 
• 135420-23-4 7-Butyryl-4-methyl-2-propyl-4H-benzo[1,4]oxazin-3-one 

Relevant academic research and scientific papers

MECHANISMS OF FREE-RADICAL REACTIONS. XIV. SELECTIVITY OF FREE-RADICAL CHLORINATION OF VALERIC ACID DERIVATIVES WITH ARYLCHLOROIODONIUM CHLORIDES

The free-radical chlorination of C4H9Y compounds with arylchloroiodonium chlorides was investigated.The reaction of the secondary C-H bonds increases as they become further from the electronegative substituent.The reaction parameters were calculated from the ratio of the β- and γ-monochlorides by means of the Taft equation.The absolute value of ρ increases with the introduction of electronwithdrawing substituents into the arylchloroiodonium chloride molecule.

Chlorination of Carboxylic Acid Derivatives. VIII. Liquid Phase Chlorination of the Aliphatic C5-Carboxylic Acids and Their Chlorides, Methyl Esters and Chloromethyl Esters with Chlorine

The chlorination of pentanoic, 3-methylbutanoic, 2-methylbutanoic and 2,2-dimethylpropanoic acids and their derivatives with chlorine in the liquid phase have been investigated.The monochloro products formed were determined by gas-liquid chromatography (GLC) and gas-liquid chromatography-mass spectrometry (GLC-MS) as their esters through the comparison with authentic samples.The deactivation of position 2 decreases in the order COCl > CO2H > CO2CH2Cl > CO2CH3, the effect of the COCl-group in pentanoic acid derivatives being 4.3 times stronger than that of the CO2CH3-group.The deactivation is smallest in 2-methylbutanoic acid derivatives owing to the electron-donating methyl group.The EI mass spectra of the methyl and chloromethyl esters have been studied in detail.