6160-67-4Relevant articles and documents
Highly regioselective and stereoselective synthesis of C-Aryl glycosidesvianickel-catalyzedortho-C-H glycosylation of 8-aminoquinoline benzamides
Shi, Wei-Yu,Ding, Ya-Nan,Zheng, Nian,Gou, Xue-Ya,Zhang, Zhe,Chen, Xi,Luan, Yu-Yong,Niu, Zhi-Jie,Liang, Yong-Min
supporting information, p. 8945 - 8948 (2021/09/10)
C-Aryl glycosides are of high value as drug candidates. Here a novel and cost-effective nickel catalyzedortho-CAr-H glycosylation reaction with high regioselectivity and excellent α-selectivity is described. This method shows great functional group compatibility with various glycosides, showing its synthetic potential. Mechanistic studies indicate that C-H activation could be the rate-determining step.
Solvent-free synthesis of glycosyl chlorides based on the triphenyl phosphine/hexachloroacetone system
Traboni, Serena,Liccardo, Federica,Bedini, Emiliano,Giordano, Maddalena,Iadonisi, Alfonso
, p. 1762 - 1764 (2017/04/13)
Glycosyl chlorides, useful as glycosyl donors in glycoside synthesis and precursors in organic synthesis, can be easily prepared under solvent-free conditions by exposing a sugar hemiacetal to an equimolar mixture of PPh3 and hexachloroacetone
Norrisolide: Total synthesis and related studies
Brady, Thomas P.,Kim, Sun Hee,Wen, Ke,Kim, Charles,Theodorakis, Emmanuel A.
, p. 7175 - 7190 (2007/10/03)
A stereoselective synthesis of (+)-norrisolide is presented. This natural product belongs to a family of marine spongiane diterpenes the structure of which is characterized by a fused γ-lactone-γ-lactol ring system attached to a bicyclic hydrophobic core.