616195-94-9Relevant academic research and scientific papers
Preparation of Solid Polyfunctional Alkynylzinc Pivalates with Enhanced Air and Moisture Stability for Organic Synthesis
Chen, Yi-Hung,Tüllmann, Carl Phillip,Ellwart, Mario,Knochel, Paul
supporting information, p. 9236 - 9239 (2017/07/24)
We report the preparation of solid and air-stable polyfunctionalized alkynylzinc pivalates from the corresponding alkynes using TMPZnOPiv (TMP=2,2,6,6-tetramethylpiperidyl) as base. These organozinc pivalates are obtained as powders under mild conditions
TETRACYCLIC INHIBITORS OF JANUS KINASES
-
Page/Page column 99, (2008/06/13)
The present invention provides compounds that modulate the activity of Janus kinases and are useful in the treatment of diseases related to activity of Janus kinases including, for example, immune-related diseases, skin disorders, myeloid proliferative disorders, cancer, and other diseases.
NOVEL IMIDAZOLE DERIVATIVES AND THEIR USE AS PHARMACEUTICAL AGENTS
-
Page/Page column 24, (2008/06/13)
Compounds of the general formula (I) are valuable therapeutics for the treatment of cancer and cancer related diseases.
Simple, short and efficient procedure for the preparation of hydroxyl- and hydroxymethyl-substituted 2,6-dichlorobenzaldehydes
Von Hirschheydt, Thomas,Voss, Edgar
, p. 2062 - 2065 (2007/10/03)
Hydroxyl- and hydroxymethyl-substituted 2,6-dichlorobenzaldehydes 1-4 have been obtained by lithiation of the corresponding TIPS-protected dichlorophenols or dichlorobenzylic alcohols followed by reaction with DMF and subsequent deprotection of the hydroxy group. Yields are high and formation of regioisomers is not observed.
2-(2,6-dichlorophenyl)-diarylimidazoles
-
Page/Page column 7, (2010/11/29)
The invention is directed to compounds of formula (I), which are valuable therapeutics for the treatment of cancer and related diseases.
