616229-97-1Relevant academic research and scientific papers
C2-symmetry-removing diphenylamine-type chiral bisoxazoline ligands as well as synthetic method and application thereof
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Paragraph 0052; 0053; 0054; 0074; 0075; 0076, (2019/10/01)
The invention discloses C2-symmetry-removing diphenylamine-type chiral bisoxazoline ligands represented by a formula 3 shown in the description, a synthetic method of the ligands and an application ofthe ligands in an asymmetric catalytic reaction. Accord
Immobilization of diphenylamine-linked bis(oxazoline) ligands and their application in the asymmetric friedel-crafts alkylation of indole derivatives with nitroalkenes
Liu, Han,Du, Da-Ming
experimental part, p. 2121 - 2131 (2010/06/15)
A diphenylamine-linked bis(oxazoline) ligand with trans-diphenyl substitution on the oxazoline rings has been immobilized onto one- to three-generation Frechet-type dendrimers and a C3-symmetric core structure. The catalytic activities and enantioselectivities of these new ligands were tested in the asymmetric Friedel-Crafts alkylation reactions of indole derivatives with, nitroalkenes. The two types of immobilized ligands exhibited similar enantioselectivities and substrate compatibilities to the free ligand trans-DPBO we reported previously. No dendrimer effect was observed in the kinetic investigation of the Frechet-type dendrimer-immobilized ligands. The in situ recycling of the catalysts was also tested to illustrate the effect of reducing catalyst loading and the efficiency of our system.
Novel aminobenzoic acid derivatives, process for preparing the same and pharmaceutical composition containing the same
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, (2008/06/13)
An aminobenzoic acid derivative represented by the formula STR1 wherein R1, R2 and R3 are defined hereinbelow, which has excellent activity for improving liver function and for potentiating and normalizing immunity; a process for preparing the same; and a pharmaceutical composition containing the same are disclosed.
