61637-68-1Relevant academic research and scientific papers
Biosynthesis of porphyrins and related macrocycles. Part 48. The rearrangement of 2H-pyrroles (pyrrolenines) related to the proposed spiro-intermediate for porphyrin biosynthesis
Hawker, Craig J.,Spivey, Alan C.,Leeper, Finian J.,Battersby, Alan R.
, p. 1509 - 1517 (2007/10/03)
It is proposed that the biosynthesis of uroporphyrinogen III 3, the parent precursor of the natural porphyrins, chlorins and corrins, involves a 2H-pyrrole (pyrrolenine) 2 as a key intermediate. Model pyrrolenines have now been used to show that (a) pyrro
Synthetic Studies Relevant to Biosynthetic Research on Vitamin B12. Part 6. Synthesis of Chlorins by a Photochemical Approach
Battersby, Alan R.,Dutton, Christopher J.,Fookes, Christopher J. R.,Turner, Simon P. D.
, p. 1557 - 1568 (2007/10/02)
A rational synthetic route to C-methylated chlorins has been developed in which a seco-chlorin is constructed and then cyclised photochemically by an 18?-electrocyclic process.The conditions of the synthesis are mild and are compatible with the base-sensi
