61655-72-9

Basic information

• Product Name: 2-Chloro-6-(dimethylamino)pyrazine
• Synonyms: 2-Chloro-6-(dimethylamino)pyrazine;2-Chloro-6-dimethylaminopyrazine;6-chloro-N,N-dimethyl-2-pyrazinamine(SALTDATA: FREE);6-chloro-N,N-diMethylpyrazin-2-aMine;6-chloro-N,N-dimethyl-2-Pyrazinamine;6-(N,N-dimethylamino)-2-chloropyrazine
• CAS NO: 61655-72-9
• Molecular Formula: C₆H₈ClN₃
• Molecular Weight: 157.6
• Mol File: 61655-72-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 248.7±35.0 °C(Predicted)
• Appearance: /
• Density: 1.252±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 0.97±0.10(Predicted)
• CAS DataBase Reference: 2-Chloro-6-(dimethylamino)pyrazine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-6-(dimethylamino)pyrazine(61655-72-9)
• EPA Substance Registry System: 2-Chloro-6-(dimethylamino)pyrazine(61655-72-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 61655-72-9(Hazardous Substances Data)

Usage

General Description

2-Chloro-6-(dimethylamino)pyrazine is a chemical compound with the molecular formula C6H8ClN3. It is an organic compound that contains a pyrazine ring with a chlorine atom and a dimethylamino group. 2-Chloro-6-(dimethylamino)pyrazine is commonly used as a building block in pharmaceutical and agrochemical synthesis, as well as in the production of dyes and pigments. It is a versatile intermediate that can undergo various chemical reactions to produce a wide range of valuable compounds. 2-Chloro-6-(dimethylamino)pyrazine is also known for its use as a reagent in organic synthesis and as a precursor for the preparation of heterocyclic compounds. 2-Chloro-6-(dimethylamino)pyrazine has potential applications in the development of new drugs, agrochemicals, and materials.

Upstream product

• 4774-14-5 2,6-dichloropyrazine 
• 506-59-2 N,N-dimethylammonium chloride 
• 124-40-3 dimethyl amine 

Downstream Products

• 136309-09-6 2-methoxy-6-dimethylaminopyrazine 

Relevant articles and documents

BIARYL DERIVATIVE AS GPR120 AGONIST

The present invention relates to a biaryl derivative expressed by the chemical formula 1, a method for producing the biaryl derivative, a pharmaceutical composition comprising same, and use of same, the biaryl derivative expressed by the chemical formula 1, as a GPR120 agonist, promoting GLP-1 generation in the gastro-intestinal tract, reducing insulin resistance in the liver, muscles and the like from anti-inflammatory activity in the macrophage, pancreatic cells and the like, and allowing effective use in prevention or treatment of inflammation or metabolic diseases such as diabetes, complications from diabetes, obesity, non-alcoholic fatty liver disease, fatty liver disease, and osteoporosis.

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Piperazinylpyrazines with central serotoninmimetic activity.

A series of 2-(1-piperazinyl)pyrazines was synthesized and evaluated for central serotonin-like activity. The most interesting member of the series, 6-chloro-2(1-piperazinyl)pyrazine (3a), had pharmacological properties characteristic of potent central serotoninmimetic activity and only weak peripheral serotoninmimetic action. Structural similarities between 3a and serotonin are discussed.