61656-62-0

Basic information

• Product Name: 1,3-Dioxolane-4-methanol, 2,2-dimethyl-, 4-nitrobenzoate
• CAS NO: 61656-62-0
• Molecular Formula: C13H15NO6
• Molecular Weight: 281.265
• Mol File: 61656-62-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,3-Dioxolane-4-methanol, 2,2-dimethyl-, 4-nitrobenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxolane-4-methanol, 2,2-dimethyl-, 4-nitrobenzoate(61656-62-0)
• EPA Substance Registry System: 1,3-Dioxolane-4-methanol, 2,2-dimethyl-, 4-nitrobenzoate(61656-62-0)

Safety Data

• Hazardous Substances Data: 61656-62-0(Hazardous Substances Data)

Upstream product

• 106268-95-5 (R)-glycidyl 4-nitrobenzoate 
• 67-64-1 acetone 
• 100-79-8 (R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol 
• 62-23-7 4-nitro-benzoic acid 
• 902-47-6 p-nitrobenzoic anhydride 
• 27913-70-8 glycerol mono-p-nitrobenzoate 

Downstream Products

• 22323-82-6 (S)-(+)-(2,2-dimethyl-[1,3]dioxolan-4-yl)methanol 
• 119555-33-8 (S)-1,2-O-isopropylidene glycerol 4-nitrobenzoate 
• 14347-78-5 1,2-O-isopropylidene-D-glycerol 

Relevant articles and documents

Selective Monoesterification of Symmetrical Diols Using Resin-Bound Triphenylphosphine

Coupling reactions to make esters and amides are among the most widely used organic transformations. We report efficient procedures for amide bond formation and for the monoesterification of symmetrical diols in excellent yields without any requirement for high dilution or slow addition using resin-bound triarylphosphonium iodide. Easy purification, low moisture sensitivity, and good to excellent yields of the products are the major advantages of this protocol.

Lipase-mediated desymmetrization of glycerol with aromatic and aliphatic anhydrides

Chirazyme L-2 (Candida antarctica) catalyzed esterification of glycerol with aromatic and aliphatic anhydrides in 1,4-dioxane is described. All the aromatic monoacylglycerols (MAGs) were produced as (R)-enantiomers, while aliphatic MAGs were obtained either as racemic mixtures or the (S)-enantiomers. The influence of substituted aromatic rings, chain length, and presence of a conjugated double bond in the acyl donor moiety on the enantiotopic selectivity as well as the efficiency of the enzyme was studied.