61657-65-6

Usage

Uses

Used in Pharmaceutical Industry:
3,5-DIBROMO-2-METHOXYBENZALDEHYDE is used as a synthetic intermediate for the development of new drugs, leveraging its antimicrobial and antifungal properties to enhance the effectiveness of pharmaceutical formulations.
Used in Agrochemical Industry:
In the agrochemical sector, 3,5-DIBROMO-2-METHOXYBENZALDEHYDE is utilized as a component in the creation of agricultural solutions, capitalizing on its ability to combat microbial and fungal infections that affect crops.
Used in Cancer Research:
3,5-DIBROMO-2-METHOXYBENZALDEHYDE is employed as a subject of study in cancer research, exploring its potential anti-cancer properties for the advancement of oncology treatments.
Used in Dye and Pigment Production:
3,5-DIBROMO-2-METHOXYBENZALDEHYDE is used as a building block in the manufacturing process of dyes and pigments, contributing to the coloration and quality of various products in different industries.

InChI:InChI=1/C8H6Br2O2/c1-12-8-5(4-11)2-6(9)3-7(8)10/h2-4H,1H3

Upstream product

• 90-59-5 3,5-Dibromosalicylaldehyde 
• 74-88-4 methyl iodide 
• 74-83-9 methyl bromide 
• 90-02-8 salicylaldehyde 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 10245-83-7 3,4,5-Tribrom-2-(3',5'-dibrom-2'-methoxyphenyl)-1H-pyrrol 
• 10245-82-6 2-(3,5-dibromo-2-methoxyphenyl)-1H-pyrrole 
• 10245-81-5 2,4-dibromo-6-(3,4,5-tribromo-1H-pyrrol-2-yl)phenol 
• 121789-61-5 2-(3,5-Dibrom-2-hydroxyphenyl)-1H-pyrrol 
• 121789-40-0 1-(3,5-Dibrom-2-methoxyphenyl)-1,4-butandion 
• 121789-69-3 2-(3,5-Dibrom-2-hydroxyphenyl)-1-methylpyrrol 
• 121789-78-4 2-(3,5-Dibrom-2-hydroxyphenyl)thiophen 
• 121789-75-1 2-(3,5-Dibrom-2-methoxyphenyl)furan 
• 121789-76-2 2-(3,5-Dibrom-2-methoxyphenyl)thiophen 
• 121789-68-2 2-(3,5-Dibrom-2-methoxyphenyl)-1-methylpyrrol 
• 121789-77-3 2-Brom-5-(3,5-dibrom-2-methoxyphenyl)thiophen 
• 121789-70-6 5-(3,5-Dibrom-2-methoxyphenyl)-2-iod-1-methylpyrrol 
• 121789-25-1 1-(3,5-Dibrom-2-methoxyphenyl)-3-(1,3-dioxolan-2-yl)-1-propanon 
• 121789-71-7 2,3,4-Tribrom-5-(3,5-dibrom-2-methoxyphenyl)-1-methylpyrrol 

Relevant academic research and scientific papers

Optimization of a binding fragment targeting the “enlarged methionine pocket” leads to potent Trypanosoma brucei methionyl-tRNA synthetase inhibitors

Potent inhibitors of Trypanosoma brucei methionyl-tRNA synthetase were previously designed using a structure-guided approach. Compounds 1 and 2 were the most active compounds in the cyclic and linear linker series, respectively. To further improve cellular potency, SAR investigation of a binding fragment targeting the “enlarged methionine pocket” (EMP) was performed. The optimization led to the identification of a 6,8-dichloro-tetrahydroquinoline ring as a favorable fragment to bind the EMP. Replacement of 3,5-dichloro-benzyl group (the EMP binding fragment) of inhibitor 2 using this tetrahydroquinoline fragment resulted in compound 13, that exhibited an EC50 of 4?nM.

NITROGENOUS CYCLIC KETONE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE

A novel compound represented by the formula (I): wherein rings A and B each represents an optionally substituted aromatic ring, or rings A and B may be bonded to each other through linking between bonds or substituents thereof to form a ring; ring C represents a nitrogenous saturated heterocycle optionally having one or more substituents besides the oxo (provided that 2,3-dioxopyrrolidine ring is excluded); R1 represents hydrogen, an optionally substituted hydrocarbon group, or an optionally substituted heterocyclic group; and-------- indicates a single bond or a double bond. It has high antagonistic activity against a tachykinin receptor, especially an SP receptor.

3,5-Dibromo-2-methoxybenzoic acid from sea sponge Didiscus sp.

3,5-Dibromo-2-methoxybenzoic acid was isolated from sea sponge Didiscus sp. The structure of the title compound was established by spectral methods, by X-ray diffraction analysis, and by comparing with a synthetic sample prepared from salicylaldehyde.