61657-65-6 Usage
Description
3,5-DIBROMO-2-METHOXYBENZALDEHYDE, with the molecular formula C8H6Br2O2, is a yellow solid chemical compound characterized by a strong odor. It serves as a crucial intermediate in the synthesis of a variety of pharmaceuticals and agrochemicals, and is recognized for its antimicrobial, antifungal, and potential anti-cancer properties. Additionally, it contributes to the production of dyes and pigments, making it a compound of considerable interest across the fields of chemistry, pharmaceuticals, and agrochemicals.
Uses
Used in Pharmaceutical Industry:
3,5-DIBROMO-2-METHOXYBENZALDEHYDE is used as a synthetic intermediate for the development of new drugs, leveraging its antimicrobial and antifungal properties to enhance the effectiveness of pharmaceutical formulations.
Used in Agrochemical Industry:
In the agrochemical sector, 3,5-DIBROMO-2-METHOXYBENZALDEHYDE is utilized as a component in the creation of agricultural solutions, capitalizing on its ability to combat microbial and fungal infections that affect crops.
Used in Cancer Research:
3,5-DIBROMO-2-METHOXYBENZALDEHYDE is employed as a subject of study in cancer research, exploring its potential anti-cancer properties for the advancement of oncology treatments.
Used in Dye and Pigment Production:
3,5-DIBROMO-2-METHOXYBENZALDEHYDE is used as a building block in the manufacturing process of dyes and pigments, contributing to the coloration and quality of various products in different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 61657-65-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,6,5 and 7 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 61657-65:
(7*6)+(6*1)+(5*6)+(4*5)+(3*7)+(2*6)+(1*5)=136
136 % 10 = 6
So 61657-65-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H6Br2O2/c1-12-8-5(4-11)2-6(9)3-7(8)10/h2-4H,1H3
61657-65-6Relevant articles and documents
Optimization of a binding fragment targeting the “enlarged methionine pocket” leads to potent Trypanosoma brucei methionyl-tRNA synthetase inhibitors
Huang, Wenlin,Zhang, Zhongsheng,Ranade, Ranae M.,Gillespie, J. Robert,Barros-álvarez, Ximena,Creason, Sharon A.,Shibata, Sayaka,Verlinde, Christophe L.M.J.,Hol, Wim G.J.,Buckner, Frederick S.,Fan, Erkang
supporting information, p. 2702 - 2707 (2017/05/29)
Potent inhibitors of Trypanosoma brucei methionyl-tRNA synthetase were previously designed using a structure-guided approach. Compounds 1 and 2 were the most active compounds in the cyclic and linear linker series, respectively. To further improve cellular potency, SAR investigation of a binding fragment targeting the “enlarged methionine pocket” (EMP) was performed. The optimization led to the identification of a 6,8-dichloro-tetrahydroquinoline ring as a favorable fragment to bind the EMP. Replacement of 3,5-dichloro-benzyl group (the EMP binding fragment) of inhibitor 2 using this tetrahydroquinoline fragment resulted in compound 13, that exhibited an EC50 of 4?nM.
3,5-Dibromo-2-methoxybenzoic acid from sea sponge Didiscus sp.
Utkina,Fedoreyev,Ilyin,Antipin
, p. 2292 - 2294 (2007/10/03)
3,5-Dibromo-2-methoxybenzoic acid was isolated from sea sponge Didiscus sp. The structure of the title compound was established by spectral methods, by X-ray diffraction analysis, and by comparing with a synthetic sample prepared from salicylaldehyde.
