61674-94-0Relevant academic research and scientific papers
Synthesis and conformational analysis of macrocyclic dilactones mimicking the pharmacophore of aplysiatoxin
Knust, Henner,Hoffmann, Reinhard W.
, p. 1871 - 1893 (2007/10/03)
A small number of macrocyclic dilactones of type 3, i.e., 9, 10, 11, and epi-11, comprising a 3,4-dihydroxypentanoic acid unit, the pharmacophore of aplysiatoxin, and a conformationally preorganized ω-hydroxynonanoic acid unit were synthesized. Conformati
Enantioselective synthesis of bicyclic compounds via catalytic 1,4-addition-ring closing metathesis
Naasz,Arnold,Minnaard,Feringa
, p. 735 - 736 (2007/10/03)
A novel three step asymmetric annulation procedure comprises a tandem catalytic enantioselective 1,4-additionallylic substitution, Grignard addition and ring closing metathesis (RCM) sequence to provide [6,6], [7,6], [8,6] and [6,7] bicyclic products with
Radical α-Allylation of Alkyl-Substituted α-(Phenylseleno)cycloalkanones
Toru, Takeshi,Okumura, Tatsuya,Ueno, Yoshio
, p. 1277 - 1280 (2007/10/02)
Irradiation and thermal reaction of 3-, 4-, or 6-alkyl-2-(phenylseleno)cycloalkanones with tributyl-2-propenyltin gave 2-allylated products in high yields.Either trans- or cis-selenocycloalkanones afforded the identical distribution of cis- and trans-ally
