61679-61-6Relevant academic research and scientific papers
Manufacture of arylacetic acids and their esters
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, (2008/06/13)
Arylacetic acids and their esters, of the formula Ar(CH2 -COOR)n (where Ar=aryl, R is H or a hydrocarbon radical, and n is 1 or 2) are manufactured by carbonylation of halomethylaryl compounds Ar(CH2 C)n (where X is Cl, Br or I) with carbon monoxide and a catalyst m+ ?Fe(O)3 NO!- (where M is an alkali metal, ammonium or one equivalent of an alkaline earth metal) in the presence of stoichiometric amounts of an inorganic base or of an alcoholate of an alcohol ROH.
