616886-01-2Relevant academic research and scientific papers
Novel class of quinone-bearing polyamines as multi-target-directed ligands to combat Alzheimer's disease
Bolognesi, Maria Laura,Banzi, Rita,Bartolini, Manuela,Cavalli, Andrea,Tarozzi, Andrea,Andrisano, Vincenza,Minarini, Anna,Rosini, Michela,Tumiatti, Vincenzo,Bergamini, Christian,Fato, Romana,Lenaz, Giorgio,Hrelia, Patrizia,Cattaneo, Antonino,Recanatini, Maurizio,Melchiorre, Carlo
, p. 4882 - 4897 (2008/03/11)
One of the characteristics of Alzheimer's disease (AD) that hinders the discovery of effective disease-modifying therapies is the multifactorial nature of its etiopathology. To circumvent this drawback, the use of multi-target-directed ligands (MTDLs) has
Useful for treating neuropraxia Alzheimer 2, 5-BIS-Dimamine-[ 1, 4] Benzoquinonimine derivative, and a method for manufacturing the same, and a method for manufacturing the intermediate body
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Page/Page column 22, (2008/06/13)
2,5-bis-diamine-[1,4]benzoquinonic derivatives, having a general formula (I) have proved useful for the treatment of Alzheimer's disease; a method for preparing them and intermediates used in said method are also described.
