61689-40-5

Usage

Heterocyclic compound

Yes
The compound contains a ring structure with more than one type of atom, specifically sulfur, nitrogen, and oxygen.

Derivative of 1,3,4-oxathiazole

Yes
It is derived from the parent compound 1,3,4-oxathiazole, which is a five-membered ring containing sulfur, oxygen, and nitrogen atoms.

Ethyl ester group

Yes
The presence of an ethyl ester group (-COOCH2CH3) increases the lipophilicity of the molecule, potentially enhancing its drug-like properties.

Used in organic synthesis

Yes
The compound serves as a building block or intermediate in the synthesis of more complex organic molecules.

Pharmaceutical research

Yes
It is utilized in the development of new drugs and biologically active molecules due to its unique structure and properties.

Potential applications

Drug development
The compound's structure and properties make it an interesting target for further chemical and pharmacological investigations, with potential applications in the development of new therapeutic agents.

Enhanced drug candidate potential

Yes

Further chemical and pharmacological investigations

Recommended
The unique structure and properties of 1,3,4-OXATHIAZOLE-5-CARBOXYLIC ACID, 2-OXO-, ETHYL ESTER warrant further research to explore its full potential in drug development and other applications.

Upstream product

• 2757-23-5 chloro(chlorosulfanyl)methanone 
• 617-36-7 Ethyl oxamate 

Downstream Products

• 61689-36-9 5-(4-chlorophenyl)-[1,2,4]thiadiazole-3-carboxylic acid ethyl ester 
• 61689-37-0 5-(4-ethoxycarbonyl-phenyl)-[1,2,4]thiadiazole-3-carboxylic acid ethyl ester 
• 61689-35-8 ethyl 5-phenyl-1,2,4-thiadiazole-3-carboxylate 
• 61689-38-1 5-p-tolyl-[1,2,4]thiadiazole-3-carboxylic acid ethyl ester 
• 851225-56-4 5-(3,4-dichloro-phenyl)-[1,2,4]thiadiazole-3-carboxylic acid ethyl ester 
• 851225-42-8 5-(4-trifluoromethoxyphenyl)[1,2,4]thiadiazole-3-carboxylic acid ethyl ester 
• 851225-36-0 5-(4-trifluoromethylphenyl)[1,2,4]thiadiazole-3-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

COMPOUNDS AND COMPOSITIONS FOR EYE TREATMENTS

This disclosure features chemical entities (e.g., a compound or a pharmaceutically acceptable salt and/or hydrate and/or prodrug of the compound) that that generates cross-linking in the cornea in response to exposure to an electromagnetic irradiation. Th

Non-ATP competitive glycogen synthase kinase 3β (GSK-3β) inhibitors: Study of structural requirements for thiadiazolidinone derivatives

The 2,4-disubstituted thiadiazolidinones (TDZD) were described as the first non-ATP competitive GSK-3β inhibitors. New modifications in this heterocyclic ring are here reported to study the influence on the biological activity. The basic skeleton of 1,2,4-thiadiazole and also one of the carbonyl groups are kept, while different modifications are introduced in positions 3 and 5, respectively. The GSK-3β activity of the new thiadiazole derivatives here synthesized showed IC50 values for some of the compounds in the micromolar range. Additionally, ATP competition studies have been carried out, showing that as well as the first generation of TDZD, these new compounds act in a non-competitive manner. With this study, additional requirements for the biological activity of the TDZD family have been delineated.

4-((Phenoxyalkyl)thio)-phenoxyacetic acids and analogs

The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR modulators to treat or inhibit the progression of, for example, dyslipidemia.

5-Aryl-1,2,4-thiadiazole-3-carboxylates and agricultural methods

Novel 5-aryl-1,2,4-thiadiazole-3-carboxylates have been found to be effective in reducing herbicidal injury to desirable plants. Said compounds are also useful in increasing the sucrose content of sugar cane.