616899-92-4Relevant academic research and scientific papers
Rapid access to trans-2,6-disubstituted piperidines: Expedient total syntheses of (-)-solenopsin A and (+)-epi-dihydropinidine
Dobbs, Adrian P.,Guesné, Sebastien J. J.
, p. 2101 - 2103 (2007/10/03)
Expedient syntheses of (-)-solenopsin A and (+)-epi-dihydropinidine are reported, the key step in both being the one-pot multicomponent aza-silyl-Prins condensation reaction to yield a trans dihydropyridine. Georg Thieme Verlag Stuttgart.
The aza-silyl-Prins reaction: A novel method for the synthesis of trans-2,6-tetrahydropyridines
Dobbs, Adrian P.,Guesné, Sebastien J. J.,Hursthouse, Michael B.,Coles, Simon J.
, p. 1740 - 1742 (2007/10/03)
Reaction of 4-trimethylsilyl-3-butenyl-1-amines with aldehydes under mild Lewis acid conditions gives substituted tetrahydropyridines in excellent yields and with excellent trans diastereoselectivity.
A versatile indium trichloride mediated Prins-type reaction to unsaturated heterocycles
Dobbs, Adrian P.,Guesne, Sebastien J. J.,Martinovic, Sasa,Coles, Simon J.,Hursthouse, Michael B.
, p. 7880 - 7883 (2007/10/03)
A versatile and high-yielding indium trichloride mediated cyclization reaction of silylated homoallylic alcohols, thiols, or amines with aldehydes or epoxides is described as a rapid route to a range of unsaturated heterocycles. The excellent diastereosel
