61702-10-1

Usage

Uses

Used in Pharmaceutical Research:
(3E)-N-(5-chloropyridin-2-yl)-3-(5-chloropyridin-2-yl)imino-isoindol-1-amine is used as a compound of interest in pharmaceutical research for its potential to contribute to the development of new drugs. Its unique structure may offer novel interactions with biological targets, leading to the discovery of new therapeutic agents.
Used in Chemical Research:
In the field of chemical research, (3E)-N-(5-chloropyridin-2-yl)-3-(5-chloropyridin-2-yl)imino-isoindol-1-amine is utilized as a subject for studying its reactivity and potential to form new chemical entities. Understanding its properties can lead to advancements in synthetic chemistry and the creation of new compounds with various applications.
Further research is necessary to fully explore the properties and potential uses of (3E)-N-(5-chloropyridin-2-yl)-3-(5-chloropyridin-2-yl)imino-isoindol-1-amine in different industries and applications.

InChI:InChI=1/C18H11Cl2N5/c19-11-5-7-15(21-9-11)23-17-13-3-1-2-4-14(13)18(25-17)24-16-8-6-12(20)10-22-16/h1-10H,(H,21,22,23,24,25)

Upstream product

• 1072-98-6 5-chloro-2-pyridylamine 
• 91-15-6 phthalonitrile 

Relevant academic research and scientific papers

Living radical polymerization of acrylates mediated by 1,3-bis(2- pyridylimino)isoindolatocobalt(II) complexes: Monitoring the chain growth at the metal

A new type of mediator for cobalt(II)-mediated radical polymerization is reported which is based on 1,3-bis(2-pyridylimino)isoindolate (bpi) as ancillary ligand. The modular synthesis of the bis(pyridylimino)isoindoles (bpiH) employed in this work is based on the condensation of 2-aminopyridines with phthalodinitriles. Reaction of the bpiH protio-ligands with a twofold excess of cobalt(II) acetate or cobalt(II) acetylacetonate in methanol gave [Co(bpi)(OAc)], which crystallize as coordination polymers, and a series of [Co(acac)(bpi)(MeOH)], which are mononuclear octahedral complexes. Upon heating the [Co(acac)(bpi)(MeOH)] compounds to 100°C under high vacuum, the coordinated methanol was removed to give the five-coordinate complexes [Co(acac)(bpi)]. The polymerization of methyl acrylate at 60°C was investigated by using one molar equivalent of the relatively short-lived radical source 2,2′-azobis(4-methoxy-2,4-dimethylvaleronitrile) (V-70) as initiator (monomer/catalyst/V-70: 600:1:1). The low solubility of the acetato complexes inhibits their significant activity as mediators in this reaction, whereas the acetylacetonate complexes control the radical polymerization of methyl acrylate more effectively. The radical polymerizations of the hexacoordinate complexes did not show a linear increase in number-average molecular weight (Mn) with conversion; however, the polydispersities were relatively low (PDI= 1.12-1.40). By using the pentacoordinate complexes [Co(acac)(bpi)] as mediators, a linear increase in Mn values with conversion, which were very close to the theoretical values for living systems, and very low polydispersities (PDI n-R] (MA: methyl acrylate; R: C(CH3)(CH2C(CH3) 2OCH3)CN), a notion also confirmed by NMR end-group analysis.