61733-90-2

Upstream product

• 102-24-9 cyclotriboric acid trimethyl ester 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 141-43-5 ethanolamine 
• 106-39-8 bromochlorobenzene 
• 121-43-7 Trimethyl borate 

Downstream Products

• 95890-53-2 2,2-bis(4-chlorophenyl)-6-methyl-4,4-tetramethylene-1,3-dioxa-4-azonia-2-boratacyclohexane 
• 95890-52-1 2,2-bis(4-chlorophenyl)-4,4-tetramethylene-1,3-dioxa-4-azonia-2-boratacyclohexane 
• 95890-54-3 2,2-bis(4-chlorophenyl)-4,4-(3-oxapentamethylene)-1,3-dioxa-4-azonia-2-boratacyclohexane 
• 95890-51-0 4,4-dibenzyl-2,2-bis(4-chlorophenyl)-1,3-dioxa-4-azonia-2-boratacyclohexane 
• 89566-59-6 di-(p-chlorophenyl)borinic acid 

Relevant academic research and scientific papers

Borinic acid catalysed peptide synthesis

The catalytic synthesis of peptides is a major challenge in the modern organic chemistry hindered by the well-established use of stoichiometric coupling reagents. Herein, we describe for the first time that borinic acid is able to catalyse this reaction under mild conditions with an improved activity compared to our recently developed thiophene-based boronic acid. This catalyst is particularly efficient for peptide bond synthesis affording dipeptides in good yields without detectable racemization.

DNA Methyltransferase inhibitors

A compound of the formula or a pharmaceutically acceptable salt thereof,whereinR1, R2, and R3 are the same or different and are independently hydrogen, lower alkyl, aryl or substituted aryl, lower alkoxy, lower alkoxyalkyl, or cycloalkyl or cycloalkyl alkoxy, where each cycloalkyl group has from 3-7 members, where up to two of the cycloalkyl members are optionally hetero atoms selected from oxygen and nitrogen, and where any member of the alkyl, aryl or cycloalkyl group is optionally substituted with halogen, lower alkyl or lower alkoxy, aryl or substituted aryl, andwhereR3 can be ribose, deoxyribose or phosphorylated derivatives thereof,whereinR1, R2, and R3 are not all hydrogen andwhereinwhen R3 is ribose, deoxyribose or phosphorylated derivatives thereof, one of R1 or R2 is not hydrogen.

Synthesis and anticoccidial activity of some azacyclo organoborinates

A series of azacyclo organoborinates derivatives of piperidinyl and pyridinyl alcohols were prepared and their anticoccidial activity was tested in vitro assay system. Among them, di(4-chlorophenyl)(2-piperidinylmethoxy-O,N)boron, di(3-trifluoromethylphenyl)(2-piperidinylmethoxy-O,N)boron, di(3-trifluoromethylphenyl)(2-pyridinylmethoxy-O,N)boron, and di(3-trifluoromethylphenyl)(2-pyridinylethoxy-O,N)boron, showed moderate anticoccidial activity against Eimeria tenella.