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Usage

Uses

Used in Flavor and Fragrance Industry:
4-methyl-3-thiophenecarboxylate is used as a flavoring agent for its distinctive sweet, fruity, and floral scent. It enhances the taste and aroma of various food products, making it a valuable component in the flavor and fragrance industries.
Used in Pharmaceutical and Agrochemical Synthesis:
4-methyl-3-thiophenecarboxylate serves as a building block in the synthesis of pharmaceuticals and agrochemicals. Its unique chemical structure allows it to be a key intermediate in the development of new drugs and agricultural chemicals, contributing to advancements in these fields.
Safety Precautions:
It is important to handle 4-methyl-3-thiophenecarboxylate with care due to its potential to cause irritation to the skin, eyes, and respiratory system. Proper safety protocols should be followed during its storage and handling to minimize risks.

Upstream product

• 73229-39-7 4-methylthiophene-3-carbonitrile 
• 30318-99-1 3-bromo-4-methylthiophene 
• 79-22-1 methyl chloroformate 
• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 

Downstream Products

• 99708-92-6 methyl 4-(bromomethyl)thiophene-3-carboxyalte 

Relevant academic research and scientific papers

MALT1 MODULATORS AND USES THEREOF

Provided herein are compounds, compositions, and methods useful for modulating MALT1 and for treating related diseases, disorders, and conditions.

INHIBITORS OF EZH2

The present invention relates to compounds that inhibit activity of the histone lysine methyltransferase, Enhancer of Zeste Homolog 2 (EZH2), pharmaceutical compositions comprising the compounds, and methods of using the compounds to treat cancer, such as hematologic and solid tumors.

ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS

This invention relates to novel compounds according to Formula (I) which are inhibitors of Enhancer of Zeste Homolog 2 (EZH2), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of cancers.

ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS

This invention relates to novel compounds according to Formula (I) which are inhibitors of Enhancer of Zeste Homolog 2 (EZH2), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of cancers.

INHIBITORS OF EZH2

The present invention relates to compounds that inhibit activity of the histone lysine N-methyltransferase, Enhancer of Zeste Homolog 2 (EZH2), pharmaceutical compositions comprising the compounds, and methods of using the compounds to treat cancer, such as hematologic and solid tumors.

ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS

This invention relates to novel compounds according to Formula (I) which are inhibitors of Enhancer of Zeste Homo log 2 (EZH2), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of cancers.

A New Synthesis of Benzothiophenes and Benzothiophenes by Annulation of Disubstituted Thiophenes

Nine newly prepared ortho-disubtituted thiophenes (1-5) react with Michael acceptors to form benzo- and benzothiophenes.This novel annulation process is specifically suited to form benzothiophenes with substituents in the benzene moiety.Substitution