61759-12-4

Upstream product

• 5707-04-0 Phenylselenyl chloride 
• 123-72-8 butyraldehyde 
• 71098-88-9 N-phenylselanylphthalimide 
• 34837-55-3 Phenylselenyl bromide 
• 1666-13-3 diphenyl diselenide 
• 82737-08-4 N-(phenylselanyl)morpholine 
• 6651-33-8 1-(trimethylsiloxy)but-1-ene 
• 121034-34-2 C₁₀H₁₂Cl₂OSe 
• 42572-42-9 phenylselenium trichloride 
• 645-96-5 Benzeneselenol 

Downstream Products

• 91890-81-2 (E)-1-Phenyl-4-phenylselanyl-hex-2-en-1-one 
• 91890-82-3 ((Z)-3-Chloro-1-ethyl-allylselanyl)-benzene 
• 91890-82-3 ((E)-3-Chloro-1-ethyl-allylselanyl)-benzene 
• 82737-12-0 1'α,α-di(phenylseleno)butanal 
• 24764-97-4 2-bromobutanal 
• 121034-34-2 C₁₀H₁₂Cl₂OSe 
• 163380-28-7 (3S,4R)-4-Allyl-3-((1R,2S)-1-hydroxy-2-phenylselanyl-butyl)-dihydro-furan-2-one 
• 163223-25-4 (3S,4R)-4-Allyl-3-((1R,2R)-1-hydroxy-2-phenylselanyl-butyl)-dihydro-furan-2-one 
• 1666-13-3 diphenyl diselenide 
• 121034-37-5 2-Chloro-2-phenylselanyl-butyraldehyde 

Relevant academic research and scientific papers

K2S2O8-promoted C-Se bond formation to construct α-phenylseleno carbonyl compounds and α,β-unsaturated carbonyl compounds

A novel K2S2O8-promoted C-Se bond formation from cross-coupling under neutral conditions has been developed. A variety of aldehydes and ketones react well using K2S2O8 as the oxidant in the absence of catalyst and afford desired products in moderate to excellent yields. This protocol provides a very simple route for the synthesis of α-phenylseleno carbonyl compounds and α,β-unsaturated carbonyl compounds.

α-Organylchalcogenation of aldehydes and ketones with diorganyl dichalcogenides promoted by K3PO4

A new catalytic method for direct α-organylchalcogenation of aldehydes and ketones has been developed. When various aldehydes and ketones were allowed to react with diorganyl dichalcogenides in the presence of K 3PO4, under mild reac

Enantioselective synthesis of α-alkyl,α-vinyl amino acids via [2,3]-sigmatropic rearrangement of selenimides

Chiral α-alkyl,α-vinyl amino acids (quaternary vinyl glycine derivatives) are prepared with high levels of enantiomeric purity by [2,3]-sigmatropic rearrangement of allylic selenimides. The required trisubstituted allylic selenides are prepared by an orga

α-Phenylselenenylation of aldehydes and ketones with diphenyl diselenide mediated by KF/Al2O3

The utility of KF/Al2O3 for the synthesis of α-phenylseleno aldehydes and ketones from the corresponding aldehydes or ketones and diphenyl diselenide has been investigated. Simple stirring of a mixture of aldehyde or ketone and diphe

KF/Al2O3 and PEG-400 as a recyclable medium for the selective α-selenation of aldehydes and ketones. Preparation of potential antimicrobial agents

2-Phenylseleno aldehydes and ketones were selectively obtained using solid-supported catalyst (KF/Al2O3) and PEG-400 as clean, recyclable medium in good to excellent yields. The method was applied in the preparation of highly functio

ORGANOCATALYSTS AND METHODS OF USE IN CHEMICAL SYNTHESIS

The present invention pertains generally to compositions comprising organocatalysts that facilitate stereo-selective reactions and the method of their synthesis and use. Particularly, the invention relates to metal-free organocatalysts for facilitation of stereo--selective reactions, and the method of their synthesis and use. These compounds have the structure of the Formulas (I) and (II). Where X is independently selected from CH2, N-Ra, O, S or C=O; Y is CH2, N-Ra, O, S or C=O, with the proviso that at least one of X or Y is CH2, and preferably both of X and Y are CH2; Ra is H, an optionally substituted C1-C12 alkyl, preferably an optionally substituted C1-C6alkyl including a C3-C6 cyclic alkyl group, or an optionally substituted aryl group, preferably an optionally substituted phenyl group; Rb is H, an optionally substituted C1-C12 alkyl, preferably an optionally substituted C1-C6 acyclic or a a C3-C6 cyclic alkyl group, CHO, N(Me)O, CO(S)Ra or the group of Formula (III). Where Rc and Rd are each independently H, F, C1, an optionally substituted C1-C20 alkyl, preferably an optionally substituted C1-C12 alkyl, more preferably a C1-C6 alkyl, and an optionally substituted aryl group, or together Rc and Rd form an optionally substituted carbocyclic or optionally substituted heterocyclic ring; R1 is OH, OR, NR'R", NHC(=O)R, NHSO2R; R2 is H, F, C1, an optionally substituted C1-C20 alkyl, preferably an optionally substituted C1-C6 alkyl, an optionally substituted aryl group or a =O group (which establishes a carbonyl group with the carbon to which =O is attached; R3 is H, OH, F, C1, Br, I, Cl, an optionally substituted C1-C20 alkyl, alkenyl or alkynyl ("hydrocarbyl") group, preferably an optionally substituted C1-C6 alkyl, or an optionally substituted aryl, such that the carbon to which R3 is attached has an R or S configuration; R is H, an optionally substituted C1-C20 alkyl, preferably an optionally substituted C1-C6 alkyl, or an optionally substituted aryl group, R' and R" are each independently H, an optionally substituted C1-C20 alkyl group, preferably an optionally substituted C1-C6 alkyl, or an optionally substituted aryl group; or together R' and R" form an optionally substituted heterocyclic, preferably a 4 to 7 membered optionally substituted heterocyclic group or an optionally substituted heteroaryl ring with the nitrogen to which R' and R" are attached; and wherein said compound is free from a metal catalyst.

Direct, facile aldehyde and ketone α-selenenylation reactions promoted by L-prolinamide and pyrrolidine sulfonamide organocatalysts

A new catalytic method for direct α-selenenylation reactions of aldehydes and ketones has been developed. The results of exploratory studies have demonstrated that L-prolinamide is an effective catalyst for α-selenenylation reactions of aldehydes, whereas

A simple and efficient L-prolinamide-catalyzed α-selenenylation reaction of aldehydes

An efficient and simple L-prolinamide-catalyzed α-selenenylation reaction of aldehydes with N-(phenylseleno)phthalimide has been developed for the efficient preparation of a-phenylselenoaldehydes. Such compounds are versatile building blocks for the synth

Use of phenylselenium trichloride for simple and rapid preparation of α-phenylselanyl aldehydes and ketones

α-Phenylselanyl aldehydes are prepared on a large scale by reaction of PhSeCl3 with the corresponding aldehydes in acetonitrile without isolation of the intermediate dichloro adducts. This method has been applied to α-phenylselanyl ketones deri

N-(Phenylseleno)Phthalimide: A Useful Reagent For The α-Selenylation Of Ketones And Aldehydes.

Α-phenylselenoketones and α-phenylselenoaldehydes are obtained with a good regioselectivity by treatment of the corresponding ketones or aldehydes with N-(phenylseleno)phthalimide and p-toluenesulfonic acid. - Key words: Ketones, α-phenylselenoketones, N-