24764-97-4

Basic information

• Product Name: 2-bromo-butyraldehyde
• Synonyms: 2-bromo-butyraldehyde;2-BroMobutanal
• CAS NO: 24764-97-4
• Molecular Formula: C₄H₇BrO
• Molecular Weight: 151.00178
• Mol File: 24764-97-4.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 235°C (rough estimate)
• Appearance: /
• Density: 1.4690
• Refractive Index: 1.4683
• CAS DataBase Reference: 2-bromo-butyraldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-butyraldehyde(24764-97-4)
• EPA Substance Registry System: 2-bromo-butyraldehyde(24764-97-4)

Safety Data

• Hazardous Substances Data: 24764-97-4(Hazardous Substances Data)

Usage

General Description

2-bromo-butyraldehyde, also known as 2-bromobutanal, is a chemical compound with the formula C4H7BrO. It is a colorless liquid with a pungent odor, and it is commonly used as a building block in organic synthesis. 2-bromo-butyraldehyde is primarily used in the production of pharmaceuticals, pesticides, and other fine chemicals. It is also used as an intermediate in the synthesis of fragrances and flavoring compounds. Additionally, it has applications in the manufacturing of plastics, dyes, and rubber chemicals. The compound is flammable and should be handled with care in a well-ventilated area.

Upstream product

• 123-72-8 butyraldehyde 
• 71-36-3 butan-1-ol 
• 61759-12-4 2-phenylselanylbutanal 
• 67-66-3 chloroform 
• 7726-95-6 bromine 
• 60-29-7 diethyl ether 
• 56249-61-7 N-butylidenebenzylamine 
• 71-43-2 benzene 
• 868-36-0 2-bromobutanal dimethyl acetal 
• 511-67-1 5,5-dibromobarbituric acid 
• 4275-07-4 N-butylideneaniline 
• 7707-71-3 butylidene-propyl-amine 
• 4461-87-4 1,1-dimethoxybutane 
• 39583-28-3 2-ethyl-3-nitro-oxirane 

Downstream Products

• 17626-73-2 5-ethylthiazole 
• 7422-95-9 1-dimethylamino-1-aza-1,3-pentadiene 
• 15729-76-7 2,5-diethylthiazole 
• 80387-13-9 2-(benzoyloxy)butanal 
• 64689-43-6 (Z)-4-Bromo-1-(4-fluoro-phenyl)-hex-2-en-1-one 
• 10045-49-5 5-ethyl-2-phenylthiazole 
• 901304-49-2 C₂₀H₂₃N₃OS 
• 39136-60-2 5-ethylthiazol-2-amine 
• 35874-97-6 α-(phenylthio)butanal 
• 92722-12-8 4-amino-N-(5-ethyl-oxazol-2-yl)-benzenesulfonamide 
• 7472-25-5 1,1-dimethoxy-butan-2-ol 
• 19961-52-5 5-ethyl-2-methylthiazole 
• 130570-57-9 4-benzyloxy-2,3-dimethyl-7-methoxyindole 

Relevant articles and documents

Catalytic Diastereoselective Hetero-Diels-Alder Reaction of α-Haloacroleins with Alkenes: Construction of 3,4-Dihydropyran

In this Letter, a catalytic diastereoselective hetero-Diels-Alder reaction of α-haloacroleins with less polarized alkenes was developed, and the resulting 3,4-dihydropyrans were produced in high yields with a broad substate scope. Mechanism studies showed that 3,4-dihydropyran was produced from the ring expansion of cyclobutane, which was generated in the ring contraction of the initially formed unstable 3,4-dihydropyran conformer.

MACROCYCLIC INHIBITORS OF HEPATITIS C VIRUS

Inhibitors of HCV replication of formula (I) and the N-oxides, salts, or stereoisomers thereof, wherein each dashed line (represented by ------) represents an optional double bond; X is N, CH and where X bears a double bond it is C; R1 is -OR6, -NH-SO2R7; R2 is hydrogen, and where X is C or CH, R2 may also be C1-6alkyl; R3 is hydrogen, C1-6alkyl, C1-6alkoxyC1-6alkyl, or C3-7cycloalkyl; n is 3, 4, 5, or 6; R4 and R5 independently from one another are hydrogen, halo, hydroxy, nitro, cyano, carboxyl, C1-6alkyl, C1-6alkoxy, C1-6alkoxyC1-6alkyl, C1-6alkylcarbonyl, C1-6alkoxy- carbonyl, amino, azido, mercapto, C1-6alkylthio, polyhaloC1-6alkyl, aryl or Het; W is aryl or Het; R6 is hydrogen; aryl; Het; C3-7cycloalkyl optionally substituted with C1-6alkyl; or C1-6alkyl optionally substituted with C3-7cycloalkyl, aryl or with Het; R7 is aryl; Het; C3-7cycloalkyl optionally substituted with C1-6alkyl; or C1-6alkyl optionally substituted with C3-7cycloalkyl, aryl or with Het; aryl is phenyl or naphthyl, each optionally substituted with 1-3 substituents; Het is a 5 or 6 membered saturated, partially unsaturated or completely unsaturated heterocyclic ring containing 1 - 4 heteroatoms each independently selected from N, O or S, and optionally substituted with 1 -3 substituents; pharmaceutical compositions containing compounds (I) and processes for preparing compounds (I). Bioavailable combinations of the inhibitors of HCV of formula (I) with ritonavir are also provided.

Polymer-supported 4-(phenylseleno)morpholine as a useful α-selenenylating agent for saturated aldehydes. A highly efficient route to α-haloaldehydes on solid phase

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