6177-84-0

Usage

Uses

Used in Toxicological Research:
3-Pentylfuran is used as a toxicological agent for studying its effects on liver and kidney function in laboratory animals, particularly mice. It helps researchers understand the mechanisms of toxicity and develop potential treatments or interventions for liver and kidney damage caused by similar compounds.
Used in Environmental Monitoring:
3-Pentylfuran can be used as an indicator of environmental contamination, as its presence in water or soil samples may suggest the presence of toxic substances or pollutants. Monitoring levels of 3-pentylfuran can help assess the quality of the environment and the potential risks to human and animal health.
Used in Pharmaceutical Development:
Although 3-pentylfuran is toxic, it may still have potential applications in the development of pharmaceuticals or other therapeutic agents. Researchers can study its chemical properties and interactions with biological systems to design safer and more effective drugs that can mitigate its toxic effects or exploit its biological activity for therapeutic purposes.

Upstream product

• 24406-16-4 lithium di-n-butylcuprate 
• 84802-88-0 3-<methyl>furan 
• 79241-42-2 2-[2-Phenylsulfanyl-eth-(Z)-ylidene]-heptan-1-ol 
• 119614-40-3 2-Ethoxy-4-pent-(Z)-ylidene-tetrahydro-furan 
• 1002-36-4 hep-2-yn-1-ol 
• 119614-35-6 1-(2-Bromo-1-ethoxy-ethoxy)-hept-2-yne 
• 3439-99-4 2-n-pentylbuta-1,3-diene 
• 79241-40-0 3,4-epoxy-3-pentyl-1-butene 
• 22037-28-1 3-bromofurane 
• 693-25-4 n-pentylmagnesium bromide 

Relevant academic research and scientific papers

Catalyst-Controlled Selective Functionalization of Unactivated C-H Bonds in the Presence of Electronically Activated C-H Bonds

A new chiral dirhodium tetracarboxylate catalyst, Rh2(S-2-Cl-5-BrTPCP)4, has been developed for C-H functionalization reactions by means of donor/acceptor carbene intermediates. The dirhodium catalyst contains four (S)-1-(2-chloro-5-bromophenyl)-2,2-diphenylcyclopropane-1-carboxylate ligands, in which all four 2-chloro-5-bromophenyl groups are on the same face of the catalyst, leading to a structure, which is close to C4 symmetric. The catalyst induces highly site selective functionalization of remote, unactivated methylene C-H bonds even in the presence of electronically activated benzylic C-H bonds, which are typically favored using earlier established dirhodium catalysts, and the reactions proceed with high levels of diastereo- and enantioselectivity. This C-H functionalization method is applicable to a variety of aryl and heteroaryl derivatives. Furthermore, the potential of this methodology was illustrated by sequential C-H functionalization reactions to access the macrocyclic core of the cylindrocyclophane class of natural products.

A Radical Cyclisation Route to 3-Alkyl Furans. Synthesis of Perillene and Dendrolasin

A general three step synthesis of 3-alkyl furans, including Perillene and Dendrolasin, from alk-2-ynyl alcohols is described via radical cyclisation of 2-bromo-1-ethoxyethyl alk-2-ynyl ethers to 2-ethoxy-4-alkylidene tetrahydrofurans.

STEREOSELECTIVE 1,4-ADDITION OF DIALKYLALUMINUM BENZENETHIOLATE TO VINYL OXIRANES

Reactions of vinyl oxiranes and diethylaluminum benzenethiolate in benzene at room temperature proceed regio- and stereoselectively to afford mainly (Z)-4-phenylthio-2-buten-1-ol derivatives in good yields.