61795-10-6Relevant academic research and scientific papers
Base promotedgem-difluoroolefination of alkyl triflones
Yang, Ren-Yin,Wang, Hui,Xu, Bo
supporting information, p. 4831 - 4834 (2021/05/25)
A new synthesis ofgem-difluoroalkenes from readily available alkyl triflones and difluorocarbene precursors such as TMSCF2Br has been reported. The reaction, regardless of electronic effect, givesgem-difluoroalkenes in good to excellent yields. The mechanism may involve deprotonation of triflones, nucleophilic addition, and the elimination of SO2CF3
A Protocol to Transform Sulfones into Nitrones and Aldehydes
Rodrigo, Eduardo,Alonso, Inés,Cid, M. Belén
supporting information, (2018/09/27)
A simple method to transform sulfones into nitrones and therefore into the corresponding carbonyl derivatives has been developed. Some examples demonstrate that it is a new reliable and versatile reaction in the toolbox of sulfones that has great synthetic potential. NMR and computational studies were used to elucidate the mechanism.
A Protocol to Transform Sulfones into Nitrones and Aldehydes
Rodrigo, Eduardo,Alonso, Inés,Cid, M. Belén
supporting information, p. 5789 - 5793 (2018/09/29)
A simple method to transform sulfones into nitrones and therefore into the corresponding carbonyl derivatives has been developed. Some examples demonstrate that it is a new reliable and versatile reaction in the toolbox of sulfones that has great synthetic potential. NMR and computational studies were used to elucidate the mechanism.
Efficient C(sp3alkyl)-SCF3 bond formations via copper-mediated trifluoromethylthiolation of alkyl halides
Lin, Quanfu,Chen, Li,Huang, Yangjie,Rong, Mingguang,Yuan, Yaofeng,Weng, Zhiqiang
, p. 5500 - 5508 (2014/07/21)
A general and convenient copper-mediated trifluoromethylthiolation of primary and secondary alkyl halides was described. Variation of the solvent, additives and time allowed optimization of the reaction. A wide range of alkyl halides were explored to give a set of alkyl trifluoromethyl thioethers in moderate to excellent yields. A variety of functional groups, including ethers, thioether, esters, nitriles, amides, and ketal groups, were well tolerated in the electrophilic partner. This journal is the Partner Organisations 2014.
