618-01-9

Usage

Uses

Used in Chemical Industry:
3,4-Dimethylbenzenesulfonic acid is used as an intermediate in the production of dyes, pigments, and pharmaceuticals for its ability to facilitate the synthesis of these complex organic compounds.
Used in Organic Synthesis:
3,4-Dimethylbenzenesulfonic acid is used as a catalyst in the synthesis of various organic compounds, enhancing the efficiency and selectivity of chemical reactions.
Used in Esterification and Condensation Reactions:
3,4-Dimethylbenzenesulfonic acid is used as a catalyst in esterification and condensation reactions, leveraging its acidic properties to promote the formation of desired products.
Used in Corrosion Inhibition:
3,4-Dimethylbenzenesulfonic acid is used as a corrosion inhibitor in industrial applications, protecting materials from degradation and extending their service life.

Upstream product

• 95-47-6 o-xylene 
• 42187-27-9 3,4-dimethyl-benzenesulfinic acid 
• 7664-93-9 sulfuric acid 
• 25241-16-1 2,3-dimethylbenzenesulfonic acid 
• 24611-77-6 2-bromo-4,5-dimethyl-benzenesulfonic acid 

Downstream Products

• 95-47-6 o-xylene 
• 615-60-1 4-chloro-1,2-dimethylbenzene 
• 343316-87-0 3,4-Dimethyl-5-nitrobenzolsulfonsaeure 
• 838840-40-7 4,5-dimethyl-2-nitro-benzenesulfonic acid 
• 343316-36-9 3,4-dimethyl-2-nitro-benzenesulfonic acid 
• 80867-75-0 2-amino-3,4-dimethylbenzenesulfonic acid 
• 38452-49-2 3,4-dimethylphenyl methyl sulfone 
• 42187-27-9 3,4-dimethyl-benzenesulfinic acid 
• 1802632-22-9 2-(tert-butoxy)-4-(3-methyl-3-(5-(methylsulfonyl)isoindolin-2-yl)butyl)phenol 
• 88-99-3 benzene-1,2-dicarboxylic acid 

Relevant academic research and scientific papers

Discovery of Investigational Drug CT1812, an Antagonist of the Sigma-2 Receptor Complex for Alzheimer's Disease

An unbiased phenotypic neuronal assay was developed to measure the synaptotoxic effects of soluble Aβ oligomers. A collection of CNS druglike small molecules prepared by conditioned extraction was screened. Compounds that prevented and reversed synaptotox

Cornforth and Corey-Suggs reagents as efficient catalysts for sulfonation of aromatic and heteroaromatic compounds using NaHSO3 under solvent free and microwave conditions

Cornforth and Corey-Suggs reagents Pyridinium Dichromate (PDC) and Pyridinium Chlorochromate (PCC) were explored as efficient catalysts for sulfonation of aromatic and heteroaromatic compounds using NaHSO3 in aqueous acetonitrile medium at room temperature within 1–4 h, while microwave assisted reactions took place within 1–4 min under solvent-free conditions. These observations indicate significant rate accelerations in microwave assisted reactions. which were explained due to the bulk activation of molecules induced by insitu generated high temperatures and pressures when microwaves are transmitted through reaction medium.

Regioselective Sulfonation of Aromatic Compounds over 1,3-Disulfonic Acid Imidazolium Chloride under Aqueous Media

1,3-Disulfonic acid imidazolium chloride ([Dsim]Cl), as a Bronsted acidic ionic liquid, is introduced for the sulfonation of aromatic compounds by in situ generation of sulfuric acid at 50 °C under mild conditions and in aqueous medium.

ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE

Isoindoline sigma-2 receptor antagonist compounds, pharmaceutical compositions comprising such compounds, and methods for inhibiting Abeta- associated synapse loss or synaptic dysfunction in neuronal cells, modulating an Abeta-associated membrane trafficking change in neuronal cells, and treating cognitive decline associated with Abeta pathology are provided.

PROCESS FOR PRODUCING TERT-LEUCINE

The present invention provides a method of producing tert-leucine, which includes reacting tert-leucine with substituted benzenesulfonic acid represented by the following formula (1) wherein R1 and R2 are each independently a hydrogen atom, an alkyl group or a halogen atom, except a compound wherein R1 and R2 are both hydrogen atoms, in a solvent, to give tert-leucine·substituted benzenesulfonate represented by the following formula (2) wherein R1 and R2 are the same substituents as above, separating the salt by crystallization and then dissociating the salt. According to the present invention, a production method of tert-leucine is provided, which includes forming a tert-leucine salt hardly soluble in a solvent and crystallization thereof to efficiently recover tert-leucine from the solvent.

A novel method for sulfonation of aromatic rings with silica sulfuric acid

Direct and chemoselective sulfonation of aromatic compounds with silica sulfuric acid in 1,2-dichloeoethane or under solvent-free conditions.