618-57-5

Basic information

• Product Name: 2-PROPYL SUCCINIC ACID
• Synonyms: 2-Propylbutanedioic acid;PROPYLSUCCINIC ACID;2-PROPYL SUCCINIC ACID;1,2-Pentanedicarboxylic acid
• CAS NO: 618-57-5
• Molecular Formula: C7H12O4
• Molecular Weight: 160.17
• Mol File: 618-57-5.mol
• Article Data: 1

Chemical Properties

• Melting Point: 100.5 °C
• Boiling Point: 265.8±13.0 °C(Predicted)
• Appearance: /
• Density: 1 +-.0.06 g/cm3(Predicted)
• PKA: 4.56±0.19(Predicted)
• CAS DataBase Reference: 2-PROPYL SUCCINIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PROPYL SUCCINIC ACID(618-57-5)
• EPA Substance Registry System: 2-PROPYL SUCCINIC ACID(618-57-5)

Safety Data

• Hazardous Substances Data: 618-57-5(Hazardous Substances Data)

Usage

Uses

2-Propylsuccinic Acid is a metabolite of valproic acid (V094750 ). Valproic acid is an anticonvulsant that acts as a mood stabilizer for those with bipolar disorder.

Upstream product

• 13074-61-8 2-propylmaleic acid 
• 5469-28-3 n-propylfumaric acid 
• 123-72-8 butyraldehyde 
• 105-56-6 ethyl 2-cyanoacetate 
• 59322-89-3 2-cyano-3-propyl-succinic acid diethyl ester 
• 78423-27-5 1,1,2-pentanetricarboxylic acid triethyl ester 
• 91691-38-2 (1-nitromethyl-butyl)-malonic acid diethyl ester 
• 14035-82-6 propylsuccinic anhydride 
• 7732-18-5 water 
• 139474-72-9 dimethyl (E)-2-(propylidene)succinate 
• 5699-72-9 1-Cyanobutanol 
• 109-52-4 valeric acid 
• 3601-52-3 opt. inakt. 4-Ethoxy-4-hydroxy-2-propyl-buttersaeure-lacton 
• 615-83-8 2-bromo-pentanoic acid ethyl ester 

Downstream Products

• 3975-88-0 D(+)-n-Propylbernsteinsaeure 
• 1518-75-8 3-n-propylthiophene 

Relevant articles and documents

Nitroalkanes and dimethyl maleate as source of 3-alkyl succinic anhydrides and (E)-3-alkylidene succinic anhydrides

Nitroalkanes react with dimethyl maleate giving a tandem Michael addition/elimination of nitrous acid. The obtained (E)-2-alkylidene dimethyl succinates are: (i) reduced to the corresponding 2-alkyl dimethyl succinates which after hydrolysis produce 1,4-dicarboxylic acids that are prone to convert into the corresponding 3-alkyl succinic anhydrides or (ii) hydrolysed to (E)-2-alkylidene-succinic acids that are easily cyclised to (E)-3-alkylidene succinic anhydrides.