618-61-1 Usage
Uses
Used in Pharmaceutical Industry:
3-METHYL-5-NITRO ANILINE is used as a chemical intermediate for the synthesis of potent BMX inhibitors. These inhibitors play a crucial role in hampering ATP catalysis, which is an essential process for cellular energy production and various cellular functions. By inhibiting ATP catalysis, BMX inhibitors can potentially disrupt the growth and proliferation of cancer cells, making them a promising target for the development of anticancer drugs.
Additionally, 3-METHYL-5-NITRO ANILINE can be used in the synthesis of other pharmaceutical compounds with various therapeutic applications, such as antimicrobial agents, anti-inflammatory drugs, and analgesics. Its unique chemical structure allows for the development of novel drug candidates with improved efficacy, safety, and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 618-61-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,1 and 8 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 618-61:
(5*6)+(4*1)+(3*8)+(2*6)+(1*1)=71
71 % 10 = 1
So 618-61-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H8N2O2/c1-5-2-6(8)4-7(3-5)9(10)11/h2-4H,8H2,1H3
618-61-1Relevant academic research and scientific papers
The Kinetics of the Reactions of Picryl Chloride with Some Substituted Anilines. Part 5.
Emokpae, Thomas A.,Eguavoen, Osa,Hirst, Jack
, p. 829 - 831 (2007/10/02)
Arrhenius parameters have been measured for the reactions of picryl chloride with the following substituted anilines in acetonitrile: 3-amino- and 3-methyl-aniline, 3-amino-5-nitroaniline, 3-fluoro-5-methylsulphonylaniline, 3-X-5-methylanilines (X=NO2, OMe, CH3, F, Cl, Br, or I) and 3,5-X2-anilines (X = F, Cl, Br, or I).A total of 33 3,5-disubstituted anilines have now been examined for the additivity of substituent effects on the free energy of activation, and it has been shown that with the exception of 3-amino-5-nitroaniline this hypothesis reproduces experimental rate constants within a factor of 2.A rationalization is proposed for the deviations that occur in some cases when more stringent criteria of additivity are used.
