618070-53-4Relevant academic research and scientific papers
Divergent synthesis of 1,3,5-tri and 1,3-disubstituted pyrazoles under transition metal-free conditions
Ma, Liyao,Ou, Pengcheng,Huang, Xueliang
supporting information, p. 6487 - 6491 (2020/11/10)
Pyrazole cores are common structural motifs existing in various agrochemicals and pharmaceuticals. Herein, a transition metal-free, three-component reaction of arylaldehydes, ethyl acrylate and N-tosylhydrazones is described, which leads to the formation of 1,3,5-trisubstituted and 1,3-disubstituted pyrazoles divergently under slightly different conditions. This journal is
