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618098-09-2

1,3-BIS(4-METHOXYPHENYL)-1H-PYRAZOL-5-AMINE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 618098-09-2 Structure

  • Basic information

    1. Product Name: 1,3-BIS(4-METHOXYPHENYL)-1H-PYRAZOL-5-AMINE
    2. Synonyms: SALOR-INT L318272-1EA;1,3-BIS(4-METHOXYPHENYL)-1H-PYRAZOL-5-AMINE
    3. CAS NO:618098-09-2
    4. Molecular Formula: C17H17N3O2
    5. Molecular Weight: 295.34
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 618098-09-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1,3-BIS(4-METHOXYPHENYL)-1H-PYRAZOL-5-AMINE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1,3-BIS(4-METHOXYPHENYL)-1H-PYRAZOL-5-AMINE(618098-09-2)
    11. EPA Substance Registry System: 1,3-BIS(4-METHOXYPHENYL)-1H-PYRAZOL-5-AMINE(618098-09-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 618098-09-2(Hazardous Substances Data)

618098-09-2 Usage

Chemical Class

Pyrazole compounds

Structure

1H-pyrazole-5-amine derivative with two 4-methoxyphenyl groups attached at the 1 and 3 positions

Applications

Pharmaceutical and research industries

Potential Uses

Therapeutic applications, biological activity, building block for synthesis of other compounds

Safety Precautions

Handle with care, use by trained professionals, follow proper safety protocols

Check Digit Verification of cas no

The CAS Registry Mumber 618098-09-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 6,1,8,0,9 and 8 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 618098-09:
(8*6)+(7*1)+(6*8)+(5*0)+(4*9)+(3*8)+(2*0)+(1*9)=172
172 % 10 = 2
So 618098-09-2 is a valid CAS Registry Number.

618098-09-2Downstream Products

618098-09-2Relevant articles and documents

Synthesis and biological evaluation of pyrazolo[3,4-b]pyridin-4-ones as a new class of topoisomerase II inhibitors

Tabrizi, Mojgan Aghazadeh,Baraldi, Pier Giovanni,Baraldi, Stefania,Prencipe, Filippo,Preti, Delia,Saponaro, Giulia,Romagnoli, Romeo,Gessi, Stefania,Merighi, Stefania,Stefanelli, Angela,Fazzi, Debora,Borea, Pier Andrea,Maia, Rodolfo Couto,Romeiro, Nelilma C.,Fraga, Carlos A.M.,Barreiro, Eliezer J.

, p. 342 - 353 (2016/10/11)

A series of 1,3,6-triphenylpyrazolo[3,4-b]pyridin-4-one derivatives was designed, synthesized and evaluated for cytotoxic activity in A375 human melanoma and human erythroleukemia (HEL) cells. The new pyrazolopyridones displayed comparable activities to the antitumor compound etoposide. The inhibitory effect of compounds 17, 18, 27 and 32 against topoisomerase II-mediated cleavage activities was measured finding good correlation with the results obtained from MTS assay. Docking studies into bacterial topoisomerase II (DNA Gyrase), topoisomerase IIα and topoisomerase IIβ binding sites in the DNA binding interface were performed.

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