618107-01-0

Upstream product

• 766-94-9 vinyl phenyl ether 
• 212902-45-9 (3R,4R)-3,4-bis(methoxymethoxy)-Δ¹-pyrroline-N-oxide 

Downstream Products

• 618107-05-4 ((2R,3R,4R)-1-Benzyl-3,4-bis-methoxymethoxy-pyrrolidin-2-yl)-acetic acid phenyl ester 

Relevant academic research and scientific papers

Simple preparation of N-benzyl-β-aminohydroxamic acids by 1,3-dipolar cycloaddition of nitrones

β-Aminohydroxamic acids 6a-d are prepared in 4 steps and 30-45% overall yield from nitrones 1a-d by 1,3-dipolar cycloaddition with phenyl vinyl ether, N-benzylation, thermal rearrangement, and nucleophilic substitution of the formed phenyl ester with hydroxylamine.