61821-54-3Relevant academic research and scientific papers
Rapid and efficient protocol for Willgerodt–Kindler’s thioacetamides catalyzed by sulfated polyborate
Rekunge, Deelip S.,Khatri, Chetan K.,Chaturbhuj, Ganesh U.
, p. 2091 - 2095 (2017/10/06)
Abstract: A simple and efficient method for the synthesis of one-pot, three-component thioacetamides via Willgerodt–Kindler reaction was developed using a sulfated polyborate catalyst. The method described the reaction of ketones, sulfur, and secondary am
Synthesis of thioamides via one-pot A3-coupling of alkynyl bromides, amines, and sodium sulfide
Sun, Yadong,Jiang, Huanfeng,Wu, Wanqing,Zeng, Wei,Li, Jianxiao
supporting information, p. 700 - 707 (2014/01/06)
We herein describe a novel method for the synthesis of thioamides by a three component condensation of alkynyl bromides, amines, and Na 2S·9H2O. The developed method is applicable for a wide range of amines and alkynyl bromides bearing different functional groups furnishing the corresponding products in moderate to excellent yields. The Royal Society of Chemistry.
