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2,6-Dichloro-N'-phenylisonicotinohydrazide, commonly known as Isoniazid, is a chemical compound that functions as an effective antibacterial agent. It is primarily used in the treatment of tuberculosis, where it inhibits the synthesis of mycolic acids, integral to the bacterial cell wall. This action results in the disruption and eventual death of the bacteria. Isoniazid is administered orally and is well-absorbed by the gastrointestinal tract, making it a first-line treatment for tuberculosis. It is often combined with other antibiotics to prevent the emergence of drug resistance, although it may also cause side effects such as liver toxicity and peripheral neuropathy.

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  • 61832-06-2 Structure
  • Basic information

    1. Product Name: 2,6-DICHLORO-N'-PHENYLISONICOTINOHYDRAZIDE
    2. Synonyms: 2,6-DICHLORO-N'-PHENYLISONICOTINOHYDRAZIDE
    3. CAS NO:61832-06-2
    4. Molecular Formula: C12H9Cl2N3O
    5. Molecular Weight: 282.13
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 61832-06-2.mol
  • Chemical Properties

    1. Melting Point: 144 °C
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2,6-DICHLORO-N'-PHENYLISONICOTINOHYDRAZIDE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2,6-DICHLORO-N'-PHENYLISONICOTINOHYDRAZIDE(61832-06-2)
    11. EPA Substance Registry System: 2,6-DICHLORO-N'-PHENYLISONICOTINOHYDRAZIDE(61832-06-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 61832-06-2(Hazardous Substances Data)

61832-06-2 Usage

Uses

Used in Pharmaceutical Industry:
Isoniazid is used as an antibacterial agent for the treatment of tuberculosis. It is utilized for its ability to inhibit the synthesis of mycolic acids, which are essential for the integrity of the bacterial cell wall, thereby leading to the death of the bacteria responsible for tuberculosis.
Used in Combination Therapy:
Isoniazid is used in combination with other antibiotics to prevent the development of drug resistance in tuberculosis treatment. This approach is crucial in managing the spread of multidrug-resistant tuberculosis strains.
Used in Research and Development:
Isoniazid serves as a subject of research for the development of new drugs and therapies targeting bacterial infections, particularly those resistant to existing treatments. Its mechanism of action and potential side effects are studied to improve its safety profile and efficacy in clinical use.

Check Digit Verification of cas no

The CAS Registry Mumber 61832-06-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,8,3 and 2 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 61832-06:
(7*6)+(6*1)+(5*8)+(4*3)+(3*2)+(2*0)+(1*6)=112
112 % 10 = 2
So 61832-06-2 is a valid CAS Registry Number.

61832-06-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,6-dichloro-N'-phenylisonicotinohydrazide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:61832-06-2 SDS

61832-06-2Downstream Products

61832-06-2Relevant articles and documents

CONTROL AGENT FOR PLANT VIRUS DISEASE CONTAINING ISONICOTINIC ACID COMPOUND

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Paragraph 0050-0051, (2020/08/13)

PROBLEM TO BE SOLVED: To provide a novel control agent for plant virus disease containing an isonicotinic acid compound or a salt thereof. SOLUTION: A control agent for plant virus disease contains an isonicotinic acid compound having, for example the following structure, or a salt thereof. SELECTED DRAWING: None COPYRIGHT: (C)2020,JPOandINPIT

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