61844-32-4

Basic information

• Product Name: 4-(2-hydroxyphenyl)butan-2-one
• CAS NO: 61844-32-4
• Molecular Formula: C₁₀H₁₂O₂
• Molecular Weight: 164.2011
• Mol File: 61844-32-4.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 278.7°C at 760 mmHg
• Flash Point: 116.6°C
• Density: 1.088g/cm³
• Vapor Pressure: 0.00248mmHg at 25°C
• Refractive Index: 1.535
• CAS DataBase Reference: 4-(2-hydroxyphenyl)butan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-hydroxyphenyl)butan-2-one(61844-32-4)
• EPA Substance Registry System: 4-(2-hydroxyphenyl)butan-2-one(61844-32-4)

Safety Data

• Hazardous Substances Data: 61844-32-4(Hazardous Substances Data)

Upstream product

• 6051-53-2 (E)-4-(2-hydroxyphenyl)but-3-en-2-one 
• 22214-28-4 4-(2-hydroxyphenyl)but-3-en-2-one 
• 90-03-9 (2-hydroxyphenyl)mercury chloride 
• 78-94-4 methyl vinyl ketone 
• 90-02-8 salicylaldehyde 
• 96013-79-5 {2-[(tert-butyldimethylsilyl)oxy]phenyl}methanol 
• 116585-12-7 2-((tert-butyldimethylsilyl)oxy)benzaldehyde 
• 1833-53-0 2-(Trimethylsilyloxy)propene 
• 917370-78-6 2-((tert-butyldiphenylsilyl)oxy)benzaldehyde 

Downstream Products

• 63449-79-6 4-(o-methoxyphenyl)-butan-2-one 
• 61844-17-5 3-hydroxy-2,3,4,5-tetrahydro-3-methyl<1>benzoxepin 
• 68118-01-4 2-hydroxymethyl-2-methylchroman 
• 1383253-06-2 (Z)-2-[(3-methyl)-3-pentenyl]phenol 
• 1019769-22-2 (6S,7S)-7-hydroxy-6-{[(S)-3-(2-hydroxyphenyl)-1-methylpropyl]amino}-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one 
• 1019768-88-7 (6R,7R)-7-hydroxy-6-{[(R)-3-(2-hydroxyphenyl)-1-methylpropyl]amino}-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1]benzazepin-2(1H)-one 
• 1019769-77-7 4-(3,5-dibromo-2-hydroxyphenyl)butan-2-one 
• 1019769-73-3 4-(2-isopropoxyphenyl)-2-butanone 

Relevant articles and documents

Dopamine D2 receptor selective agonist and application thereof

The invention relates to a dopamine D2 receptor selective agonist and application thereof. Specifically, the invention discloses an agonist with selectivity to DRD2 and discloses a potential application value of the agonist in disease treatment. The invention discloses an agonist with DRD2 selectivity for the first time, and the specific targeting DRD2 of the agonist can play a role in treating low dopamine related diseases such as Parkinson's disease, attention deficit hyperactivity disorder, pituitary adenoma, hyperprolactinemia, hyperactivity leg syndrome, negative schizophrenia and the like while side effects are reduced to the maximum extent.

Decarboxylative Csp3-Csp3 coupling for benzylation of unstable ketone enolates: Synthesis of: P -(acylethyl)phenols

A new decarboxylative Csp3-Csp3 coupling approach for the benzylation of ketone enolates has been developed. A variety of raspberry ketone derivatives were conveniently synthesized in good to excellent yields under mild conditions. A crossover reaction shed light on the mechanism of this tandem reaction.

Pd(II)-catalyzed asymmetric Wacker-type cyclization for the preparation of 2-vinylchroman derivatives with biphenyl tetraoxazoline ligands

This article describes an efficient method for the preparation of chiral chroman derivatives by the Pd(II)-catalyzed asymmetric Wacker-type cyclization using a chelation-induced axially chiral tetraoxazoline ligand. Under the optimized conditions, up to 80% yield and up to 92% ee were obtained. This is the first example to utilize o-trisubstituted 3-butenylphenols as substrates in such transformation.