61853-43-8Relevant academic research and scientific papers
Bentonite catalyzed an efficient and green synthesis of arylidene meldrum's acid derivatives in aqueous media
Yahyazadehfar, Mahdieh,Ahmadi, Sayed Ali,Sheikhhosseini, Enayatollah,Ghazanfari, Dadkhoda
, p. 513 - 519 (2021/07/25)
In the present paper, a simple, highly efficient, and environmentally friendly protocol was proposed for the Knoevenagel condensation reaction of aromatic aldehydes using Meldrum’s acid (2,2-dimethyl-4,6-dioxo-1,3-dioxane) with bentonite as an available n
Microwave-associate synthesis of Co3O4 nanoparticles as an effcient nanocatalyst for the synthesis of arylidene barbituric and Meldrum's acid derivatives in green media
Yahyazadehfar, Mahdieh,Sheikhhosseini, Enayatollah,Ahmadi, Sayed Ali,Ghazanfari, Dadkhoda
, (2019/08/02)
In this study, Co3O4 nanocatalysts were constructed in environmentally appropriate conditions using controlled, effective, and facile microwave method. The final nanostructures were characterized by SEM, XRD, and TEM analyses. The products had a small size distribution, homogeneous morphology, and crystallographic structures associated with the formation of Co3O4 nanostructures. Moreover, EDS mapping analysis confirmed the existence of Co and O elements in the final structure, and the magnetic properties of the samples were investigated by VSM. The application of this nanostructure in a catalytic process was further examined, and the results suggested that it could be used as a novel candidate for the synthesis of arylidene barbituric and Meldrum,s acid through Knoevenagel condensation of aldehydes by barbituric and Meldrum,s acid in aqueous media. The high yield of these nanocatalysts would be justified by the nature of the nanostructure as well as the experimental procedure developed in this study, which affected the physicochemical features of the products.
Discovery and preliminary SAR of 5-arylidene-2,2-dimethyl-1,3-dioxane-4,6- diones as platelet aggregation inhibitors
El Maatougui, Abdelaziz,Azuaje, Jhonny,Coelho, Alberto,Yaziji, Vicente,Carbajales, Carlos,Sotelo, Eddy,Lopez, Carmen,Cano, Ernesto,Yanez, Matilde
, p. 551 - 554,4 (2020/08/31)
We herein document the discovery of 5-arylidene-2,2-dimethyl-1,3-dioxane-4, 6-diones as a novel family of platelet aggregation inhibitors. The preliminary optimization study enabled us to establish the most salient features of the structure-activity relat
A novel light induced Knoevenagel condensation of Meldrum's acid with aromatic aldehydes in aqueous ethanol
Ghosh, Somnath,Das, Jhantu,Chattopadhyay, Subhagata
experimental part, p. 2869 - 2872 (2011/06/21)
A highly efficient environment-friendly photochemical methodology has been developed for the condensation of Meldrum's acid with aromatic aldehydes in water-ethanol solution sans any catalyst, support or promoter.
Reactions of methoxybenzylidene derivatives of 2,2-dimethyl-1,3-dioxane-4, 6-dione and their saturated analogs with certain nucleophilic reagents
Tetere,Ravina,Rijkure,Zicane
scheme or table, p. 1449 - 1453 (2011/12/16)
The reactions of the methoxybenzylidene derivatives of 2,2-dimethyl-1,3- dioxane-4,6-dione and their saturated analogs with potassium hydroxide in methanol, ammonia, and hydrazine hydrate were realized. The 1,2- bis(methoxybenzylidene)hydrazines, amides,
Knoevenagel condensation of aldehydes with Meldrum's acid in ionic liquids
Tahmassebi, Daryoush,Wilson, Levi J. A.,Kieser, Jerod M.
experimental part, p. 2605 - 2613 (2009/12/04)
The Knoevenagel condensation of Meldrum's acid with aromatic aldehydes proceeded efficiently in the recyclable ionic liquid [bmim]BF4 at room temperature in the presence of catalytic amounts of piperidine.
SYNTHESIS OF 3-CARBOXYCOUMARINS FROM O-METHOXYBENZYLIDENE MELDRUM'S ACID DERIVATIVES
Armstrong, Veronica,Soto, Oriana,Valderrama, Jaime A.,Tapia, Ricardo
, p. 717 - 726 (2007/10/02)
Reaction of o-methoxybenzaldehydes with Meldrum's acid followed by cyclization in sulfuric acid of the benzylidene derivatives 3a-g affords 3-carboxycoumarins in excellent yields.
