61857-83-8

Usage

Uses

Used in Organic Synthesis:
2,2-DIMETHYL-5-THIOPHEN-3-YL-[1,3]DIOXANE-4,6-DIONE is used as an intermediate in the production of various organic compounds due to its versatile chemical structure and reactivity.
Used in Pharmaceutical Industry:
2,2-DIMETHYL-5-THIOPHEN-3-YL-[1,3]DIOXANE-4,6-DIONE is used as a potential candidate for drug development, as it may possess biological activity and contribute to the discovery of new therapeutic agents.
Used in Materials Science:
2,2-DIMETHYL-5-THIOPHEN-3-YL-[1,3]DIOXANE-4,6-DIONE is used in the development of novel materials for electronic devices and sensors, thanks to the electronic and optical properties imparted by the presence of the thiophene ring in its structure.

InChI:InChI=1/C10H10O4S/c1-10(2)13-8(11)7(9(12)14-10)6-3-4-15-5-6/h3-5,7H,1-2H3

Upstream product

• 67-64-1 acetone 
• 21080-92-2 2-(thiophen-3-yl)malonic acid 

Relevant academic research and scientific papers

Palladium-Catalyzed Asymmetric Allylic Alkylation of 4-Substituted Isoxazolidin-5-ones: Straightforward Access to β2,2-Amino Acids

We report here an unprecedented and highly enantioselective palladium-catalyzed allylic alkylation applied to 4-substituted isoxazolidin-5-ones. Ultimately, the process provides a straightforward access to β2,2-amino acids bearing an all-carbon quaternary stereogenic center in great yields and a high degree of enantioselectivity.

The synthesis method of intermediate sodium card Xilin

The invention discloses a synthesis method of ticarcillin disodium intermediate 2,2-dimethyl-5-(3-thienyl)-4,6-dione-1,3-dioxane. The synthesis method comprises the following steps: mixing thiophenemalonic acid with acid anhydride at the temperature of 10 DEG C to 60 DEG C, and then adding dimethyl sulfoxide; and adding acetone under the action of an inorganic acid, and then carrying out hydrolysis under acidic conditions to obtain the intermediate. The synthesis method has the advantages that: the operation is simple and convenient, the environmental pollution is small, the yield is more than 80% and the purity is up to 99.8%.

Intermediates for preparing α-carboxy-α-(3-thienyl)penicillin and cephalosporin derivatives

A new process is disclosed for the preparation of alpha-carboxy-alpha-phenyl(or 3-thienyl)penicillin and cephalosporin derivatives. The process comprises reacting a 1.3-dioxane-4.6-dione derivative with the desired penicillanic or cephalosporanic acid derivative.