6188-86-9

Basic information

• Product Name: 6-Methyl-5,6,7,8-tetrahydrodibenz[c,e]azocine
• Synonyms: 6-Methyl-5,6,7,8-tetrahydrodibenz[c,e]azocine
• CAS NO: 6188-86-9
• Molecular Formula: C₁₆H₁₇N
• Molecular Weight: 223.31
• Mol File: 6188-86-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 363.8±11.0 °C(Predicted)
• Appearance: /
• Density: 1.050±0.06 g/cm3(Predicted)
• PKA: 8.68±0.20(Predicted)
• CAS DataBase Reference: 6-Methyl-5,6,7,8-tetrahydrodibenz[c,e]azocine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Methyl-5,6,7,8-tetrahydrodibenz[c,e]azocine(6188-86-9)
• EPA Substance Registry System: 6-Methyl-5,6,7,8-tetrahydrodibenz[c,e]azocine(6188-86-9)

Safety Data

• Hazardous Substances Data: 6188-86-9(Hazardous Substances Data)

Upstream product

• 6630-33-7 ortho-bromobenzaldehyde 
• 95755-52-5 (2-Bromo-benzyl)-[2-(2-iodo-phenyl)-ethyl]-amine 
• 791544-33-7 [2-(2-Bromo-phenyl)-ethyl]-(2-iodo-benzyl)-amine 
• 66384-49-4 N-(2-(2-iodophenyl)ethyl)amine 
• 65185-58-2 2-(2-bromophenyl)ethanamine 
• 65185-64-0 o-Brom-N-(o'-brombenzyl)phenaethylamin 
• 26260-02-6 2-iodobenzaldehyde 
• 116760-14-6 (2-Bromo-benzyl)-[2-(2-iodo-phenyl)-ethyl]-methyl-amine 
• 116787-32-7 [2-(2-Bromo-phenyl)-ethyl]-(2-iodo-benzyl)-methyl-amine 

Relevant articles and documents

A Convenient Synthesis of Apogalanthamine Analogues as α-Adrenergic Blocking Agents using Zerovalent Nickel

The apogalanthamine analogues, 5,6,7,8-tetrahydrodibenzazocine (2) and its N-methyl and N-acetyl derivatives (1 and 3), and the methoxy derivatives (4, 5 and 9) of (1) were obtained in good yields by cyclization of the corresponding halogeno-N-benzyl-β-phenethylamines (10a, 11a-d, 12a,b and 13a-c) using stoichiometric amounts of zerovalent nickel generated in situ and potassium iodide.