61881-11-6Relevant articles and documents
Copper-catalyzed three component C[sbnd]S/C[sbnd]N coupling for the synthesis of trifluorothioacetamides
Hu, Bo-Lun,Song, Yi-Kang,Yao, Zengwen,Zhang, Guoqiang,Zhang, Xing-Guo
, (2020/10/06)
A copper-catalyzed three component C[sbnd]S/C[sbnd]N coupling reaction of imines with sulfur and CFC-113a was developed. The reaction involves amination and C[dbnd]S double bond formation of CFC-113a, leading to biologically important trifluorothioacetamides. The method features efficient construction of trifluorothioacetyl moiety from cheap sulfur and CFC-113a, and safe disposal for environmentally persistent Freon
Switching reaction pathways of trifluoromethylated thiobenzanilides by choice of different oxidative systems
Zhu, Jiangtao,Xie, Haibo,Li, Shan,Chen, Zixian,Wu, Yongming
body text, p. 306 - 309 (2011/06/20)
Trifluoromethylated thiobenzanilides are efficiently converted to 2-trifluoromethylbenzothiazoles via intramolecular oxidative cyclization under CAN/NaHCO3 oxidation, while the dimerized products with "-S-S-" bond linkage are obtained when PIDA
Trifluoromethylation of heterocumulenes with trimethyl(trifluoromethyl)silane in the presence of fluoride ions: Synthesis of trifluoroacetamides and trifluorothioacetamides from isocyanates and isothiocyanates
Kirij, Nataliya V.,Yagupolskii, Yurii L.,Petukh, Nataliya V.,Tyrra, Wieland,Naumann, Dieter
, p. 8181 - 8183 (2007/10/03)
Trimethyl(trifluoromethyl)silane reacts in the presence of fluoride ions with isocyanates and isothiocyanates under mild conditions to give corresponding trifluoroacetamides and trifluorothioacetamides in high yields.