618905-84-3Relevant articles and documents
New and clean synthesis of N-substituted pyrroles under microwave irradiation
Aydogan, Feray,Basarir, Mehmet,Yolacan, Cigdem,Demir, Ayhan S.
, p. 9746 - 9750 (2008/02/12)
N-Substituted homochiral pyrrole derivatives were synthesized by the ring-closure reaction of cis-1,4-dichloro-2-butene with various amine compounds on a silica surface under microwave irradiation.
A new class of optically active pyrrole derivatives: (3R)-3-(pyrrol-1-yl)alk-1-enes from D-α-aminoacids
Settambolo, Roberta,Guazzelli, Giuditta,Mengali, Lucia,Mandoli, Alessandro,Lazzaroni, Raffaello
, p. 2491 - 2493 (2007/10/03)
(3R)-3-(Pyrrol-1-yl)but-1-ene 4a, (3R)-4-methyl-3-(pyrrol-1-yl)pent-1-ene 4b, (3R)-3-(pyrrol-1-yl)hex-1-ene 4c in high enantiomeric excess (>92%) were prepared starting from D-α-amino acids. The crucial steps in the synthesis, reduction (DIBAH) of the corresponding pyrrolylesters to the corresponding pyrrolylaldehydes followed by Wittig olefination proceeded without compromising the stereochemical integrity.