61895-10-1

Basic information

• Product Name: 4-Amino-3,4-dihydro-2H-naphthalen-1-one
• Synonyms: 4-Amino-3,4-dihydro-2H-naphthalen-1-one;4-aMino-3,4-dihydronaphthalen-1(2H)-one hydrobroMide;1(2H)-Naphthalenone, 4-amino-3,4-dihydro-;4-AMINO-3,4-DIHYDRONAPHTHALEN-1(2H)-ONE HBR;4-amino-3,4-dihydronaphthalen-1(2H)-one
• CAS NO: 61895-10-1
• Molecular Formula: C₁₀H₁₁NO
• Molecular Weight: 161
• EINECS: 604-604-1
• Mol File: 61895-10-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 284.0±39.0 °C(Predicted)
• Appearance: /
• Density: 1.148±0.06 g/cm3(Predicted)
• PKA: 8.07±0.20(Predicted)
• CAS DataBase Reference: 4-Amino-3,4-dihydro-2H-naphthalen-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Amino-3,4-dihydro-2H-naphthalen-1-one(61895-10-1)
• EPA Substance Registry System: 4-Amino-3,4-dihydro-2H-naphthalen-1-one(61895-10-1)

Safety Data

• Hazardous Substances Data: 61895-10-1(Hazardous Substances Data)

Usage

General Description

4-Amino-3,4-dihydro-2H-naphthalen-1-one, also known as 4-Amino-1-tetralone, is an organic compound with the molecular formula C??H??NO. It is a derivative of naphthalene and is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. It possesses a naphthalene ring with an amino group at the 4th position and a carbonyl group at the 1st position. 4-Amino-3,4-dihydro-2H-naphthalen-1-one is known for its potential as an important building block in the production of numerous biologically active compounds. Overall, 4-Amino-3,4-dihydro-2H-naphthalen-1-one has a wide range of applications in the pharmaceutical and chemical industries due to its versatile reactivity and potential for biological activity.

Upstream product

• 71545-99-8 4-bromo-3,4-dihydronaphthalen-1(2H)-one 
• 1313021-93-0 tert-butyl N-(4-oxo-1,2,3,4-tetrahydro-1-naphthalenyl)carbamate 
• 1106767-77-4 4-azido-3,4-dihydro-2H-naphthalen-1-one 
• 67614-68-0 N-(4-oxo-1,2,3,4-tetrahydro-1-naphthalenyl)acetamide 
• 62089-80-9 (-)-N-(1,2,3,4-tetrahydro-4-oxo-1-naphthyl)formamide 
• 2216-69-5 1-Methoxynaphthalene 

Downstream Products

• 1313021-98-5 4-[2-cyclohexenyl(methyl)amino]-1,2,3,4-tetrahydro-1-naphthalenone 
• 1313021-99-6 4-[allyl(2-cyclohexenyl)amino]-1,2,3,4-tetrahydro-1-naphthalenone 
• 1313022-00-2 4-[benzyl(2-cyclohexenyl)amino]-1,2,3,4-tetrahydro-1-naphthalenone 
• 1313022-01-3 4-[2-cyclohexenyl(4-methylbenzyl)amino]-1,2,3,4-tetrahydro-1-naphthalenone 
• 1313022-03-5 4-[2-cyclohexenyl(2-naphthylmethyl)amino]-1,2,3,4-tetrahydro-1-naphthalenone 
• 1313021-94-1 4-(2-cyclohexenylamino)-1,2,3,4-tetrahydro-1-naphthalenone 

Relevant articles and documents

Novel mast cell-stabilising amine derivatives of 3,4-dihydronaphthalen- 1(2H)-one and 6,7,8,9-tetrahydro-5H-benzo[7]annulen-5-one

In an investigation of 4-amino-3,4-dihydronaphthalen-1(2H)-ones as novel modulators of allergic and inflammatory phenomena, we have investigated a series of cyclic analogues. Tertiary amines of structural types 9, 10, 20 and 21 were synthesised and evaluated for mast cell stabilising activity. In vitro and in vivo studies showed that of these compounds, the cyclohexenylamino derivatives of tetralone and benzosuberone of series 20 and 21 exhibited interesting activity both in vitro and in vivo.

Synthesis of 1,2,3,4-tetrahydro-4-oxo-[or oxy-]-1-naphthylureas as novel growth-promoting compounds for animals

This invention relates to novel 1,2,3,4-tetrahydro-4-oxo-[-oxy-]-1-naphthylurea compounds and their derivatives. This invention also relates to method for the preparation of said compounds. This invention further relates to methods for the use of said tetrahydro-4-oxo-[oxy-]-1-naphthylurea compounds as animal growth regulators.

1-Benzoyl-3-(1,2,3,4-tetrahydro-4-oxo-1-naphthyl)-urea, a novel and useful intermediate for the preparation of animal growth promoting agents

This invention relates to 1-benzoyl (and 1-substituted benzoyl)-3-(1,2,3,4-tetrahydro-4-oxo-1-naphthyl)ureas, novel and useful intermediates for the preparation of 1,2,3,4-tetrahydro-4-oxo-1-naphthylurea and certain derivatives thereof. The above tetrahydro-4-oxo-1-naphthyl-urea and certain derivatives thereof are animal growth promoting agents. This invention further relates to methods of preparation of said 1-benzoyl (and 1-substituted benzoyl) 3-(1,2,3,4-tetrahydro-4-oxo-1-naphthyl)ureas.