61941-66-0

Upstream product

• 61941-62-6 2-amino-3-(4-chlorobenzoyl)benzeneacetic acid, sodium salt 
• 75-03-6 ethyl iodide 

Downstream Products

• 102414-25-5 2-amino-3-[(4-chlorophenyl)hydroxymethyl]benzeneethanol 
• 102414-29-9 <2-amino-3-(2-hydroxyethyl)phenyl>(4-chlorophenyl)methanone 
• 126849-28-3 3-(4-chlorobenzoyl)-2-<<(trifluoromethyl)carbonyl>amino>benzeneacetic acid, ethyl ester 

Relevant academic research and scientific papers

Antiinflammatory Agents. 4. Syntheses and Biological Evaluation of Potential Prodrugs of 2-Amino-3-benzoylbenzeneacetic Acid and 2-Amino-3-(4-chlorobenzoyl)benzeneacetic Acid

A series of potential prodrugs of 2-amino-3-benzoylbenzeneacetic acid (amfenac) and 2-amino-3-(4-chlorobenzoyl)benzeneacetic acid were synthesized and evaluated for their cyclooxygenase inhibiting properties, antiinflammatory potency, and gastrointestinal irritation liability.One compound, 2-amino-3-(4-chlorobenzoyl)benzeneacetamide, possessed a therapeutic index 1 order of magnitude greater than that of indomethacin.

Anti-inflammatory methods using 2-amino-3-(5- and 6-)benzoylphenylacetic acids, esters and metal salts thereof and the compounds

Novel 2-amino-3-(5- and 6-)benzoylphenylacetic acids, esters and metal salts of the formula: STR1 wherein R is hydrogen or lower alkyl, R1 is hydrogen, lower-alkyl, sodium or potassium, R2 is hydrogen, halogen or lower alkoxy, X is h