61963-01-7Relevant academic research and scientific papers
Two-step synthesis of 3-aryl-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-ones
Scott, Jeremy P.
, p. 2083 - 2086 (2008/02/05)
One-pot tandem palladium-catalysed amination and intramolecular amidation of tert-butyl (2-chloropyridin-3-yl)carbamate with substituted primary anilines allows for the preparation of 3-arylated 1,3-dihydro-2H-imidazo[4,5-b]pyridin-2- ones (49-90% yield)
Imidazo pyridine-2-ones and pharmaceutical compositions and methods of treatment utilizing same
-
, (2008/06/13)
1,3-Dihydroimidazo[4,5-b]pyridin-2-ones and corresponding thiones have utility as analgesic, antipyretic and antiinflammatory agents. They are generally prepared by treatment of a 2,3-diaminopyridine with phosgene or thiosphosgene followed by further substitution if desired.
