61964-70-3Relevant academic research and scientific papers
Substituted azetidinones
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, (2008/06/13)
Substituted azetidine intermediates for preparing novel bicyclic β-lactam penicillin analogs which have antibacterial activity are disclosed.
Methods and intermediates for preparing cis-4-oxoazetidine intermediates
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, (2008/06/13)
The stereospecific cycloaddition of nitrogen containing acetic acid halides or anhydrides with Schiff bases having a carbalkoxy group substituted on the methine carbon atom offers new intermediates and methods for preparing synthetic cephalosporin congeners having antibacterial activity.
Monocyclic beta-lactams with antibacterial activity
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, (2008/06/13)
A monocyclic β-lactam containing a cis-β-acylamino moiety as in the penicillin and cephalosporin antibacterials is disclosed. These compounds have antibacterial activity against a variety of Gram-positive and Gram-negative organisms. Intermediates useful
8-Oxo-4-thia-1-azabicyclo (4.2.0)-oct-2-ene derivatives
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, (2008/06/13)
Novel bicyclic β-lactams and intermediates useful in their preparation are disclosed. In particular, 7β-acyl-amino- and 7β-amino-8-oxo-4-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acids are prepared. The acylated compounds are antibacterial agents.
Cis-4-oxoazetidine intermediates and methods of preparing them
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, (2008/06/13)
The stereospecific cycloaddition of nitrogen containing acetic acid halides or anhydrides with Schiff bases having a carbalkoxy group substituted on the methine carbon atom offers new intermediates and methods for preparing synthetic cephalosporin congeners having antibacterial activity.
