SEPHAROSE CL-4B is a crosslinked agarose gel filtration base matrix that serves as a versatile platform for various applications in the field of biotechnology and pharmaceuticals. It is particularly known for its ability to be coupled with affinity ligands, making it a valuable tool for separation and purification processes.

61970-08-9

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Basic information
1. Product Name: SEPHAROSE CL-4B
2. Synonyms: Agarose beads 4% B-CL (Cross-l;Agarose beads 4% B-CL (Cross-linked);SEPHAROSE(R) CL-4B;SEPHAROSE CL-4B;sepharose(R) cl-4B for chromatography
3. CAS NO:61970-08-9
4. Molecular Formula: C18H19N5O
5. Molecular Weight: 321.37636
6. EINECS: N/A
7. Product Categories: Gel Filtration Media;Gel Filtration MediaResins&LC Separation Media;Protein Chromatography;Sepharose;Gel Filtration Chromatography
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: 100℃
3. Flash Point: 38 °C
4. Appearance: /
5. Density: 1.040
6. Refractive Index: N/A
7. Storage Temp.: 2-8°C
8. Solubility: N/A
9. CAS DataBase Reference: SEPHAROSE CL-4B(CAS DataBase Reference)
10. NIST Chemistry Reference: SEPHAROSE CL-4B(61970-08-9)
11. EPA Substance Registry System: SEPHAROSE CL-4B(61970-08-9)
Safety Data
1. Hazard Codes: Xi
2. Statements: 10-36/37/38
3. Safety Statements: 16-26-36-24/25-23
4. RIDADR: UN 1170 3/PG 2
5. WGK Germany: 1
6. RTECS:
7. HazardClass: 3
8. PackingGroup: N/A
9. Hazardous Substances Data: 61970-08-9(Hazardous Substances Data)

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61970-08-9 Usage

Uses

Used in Biotechnology Industry:
SEPHAROSE CL-4B is used as a gel filtration matrix for the purification of biomolecules, such as proteins, peptides, and nucleic acids. Its porous structure allows for the separation of molecules based on their size, making it an essential tool in the purification process.
Used in Pharmaceutical Industry:
SEPHAROSE CL-4B is used as a support matrix for the development of affinity chromatography systems. By coupling specific affinity ligands to the matrix, it enables the selective binding and separation of target molecules, which is crucial in the production and purification of therapeutic agents.
Used in Research and Development:
SEPHAROSE CL-4B is used as an experimental tool for studying the interactions between biomolecules and their respective ligands. This helps researchers understand the binding properties and mechanisms of various molecules, which can be applied to the development of new drugs and therapies.
Used in Diagnostic Applications:
SEPHAROSE CL-4B is used as a component in the development of diagnostic assays and tests. Its ability to separate and purify specific molecules makes it a valuable tool in the creation of accurate and reliable diagnostic tools for various medical conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 61970-08-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,1,9,7 and 0 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 61970-08:
(7*6)+(6*1)+(5*9)+(4*7)+(3*0)+(2*0)+(1*8)=129
129 % 10 = 9
So 61970-08-9 is a valid CAS Registry Number.

61970-08-9 Well-known Company Product Price

Brand
(Code)Product description
CAS number
Packaging
Price
Detail

Alfa Aesar
(H32305) Agarose beads 4% B-CL (Cross-linked)
61970-08-9
1000ml
5623.0CNY
Detail

Sigma
(CL4B200) Sepharose^® CL-4B Cross-linked
61970-08-9
CL4B200-100ML
4,506.84CNY
Detail

Sigma
(CL4B200) Sepharose^® CL-4B Cross-linked
61970-08-9
CL4B200-1L
22,534.20CNY
Detail

61970-08-9Upstream product

61970-08-9Downstream Products

61970-08-9Related news

A study on heterogeneity in molecular species of shark cartilage chondroitin sulfate C. Fractionation of the polysaccharide on SEPHAROSE CL-4B (cas 61970-08-9) in the presence of high concentrations of ammonium sulfate07/17/2019

Shark cartilage chondroitin surfate C was fractionated by chromatography on Sepharose CL-4B-2.5 to 1.5m ammonium sulfate in 10mm hydrochloric acid at 4°. Both unit-disaccharide composition and molecular-size distribution clearly affected the fractionation. Comparison of this fractionation with ...detailed

Comparison of different ligand densities in immunoaffinity chromatography of the plantibody HB-01 coupled to SEPHAROSE CL-4B (cas 61970-08-9) to purify the rHBsAg07/13/2019

This paper evaluates the immunopurification behavior of a plantibody HBsAg specific plantibody coupled to Sepharose CL-4B at different ligand densities. Results show no significant differences in the adsorption and elution capacities, and rHBsAg recovery of immunosorbents at 3.43, 4.45, and 5.31...detailed

Separation of heparin on SEPHAROSE CL-4B (cas 61970-08-9) in the presence of high concentrations of ammonium sulphate07/12/2019

Heparin was fractionated by chromatography on Sepharose CL-4B/3.8–2.0 M ammonium sulphate in 0.01 M hydrochloric acid at 4°C based on a principle different from that of gel filtration —possibly due to multiple interaction mechanisms including those based on hydrophobic bonds. The results of t...detailed

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