61981-79-1

Usage

Class

Benzimidazoles

Structure

Benzene ring fused to an imidazole ring

Substitution

Ethanamine group at the first position, methyl group at the second position

Potential applications

Pharmaceutical research and drug development

Unique features

Structural features and potential biological activities associated with benzimidazole derivatives

Additional research

Necessary to explore potential uses and properties in various scientific and industrial fields.

InChI:InChI=1/C10H13N3/c1-8-12-9-4-2-3-5-10(9)13(8)7-6-11/h2-5H,6-7,11H2,1H3

Upstream product

• 102029-12-9 N-[2-(2-methyl-benzimidazol-1-yl)-ethyl]-phthalimide 
• 51138-16-0 N-(2-nitrophenyl)ethylenediamine 
• 101285-09-0 N-[2-(2-amino-anilino)-ethyl]-phthalimide 
• 101117-96-8 N-[2-(2-nitro-anilino)-ethyl]-phthalimide 
• 111065-64-6 N-[2-(N-acetyl-2-acetylamino-anilino)-ethyl]-phthalimide 
• 615-15-6 2-Methyl-1H-benzimidazole 
• 870-24-6 2-chloroethanamine hydrochloride 
• 2472-88-0 tetrabutylammonium sulfate 

Downstream Products

• 1616961-15-9 4-(diethylamino)-N-(2-(2-methyl-1H-benzo[d]imidazol-1-yl)ethyl)benzamide 
• 279237-31-9 1,1-dimethyl 1-[(cyclohexylamino)carbonyl]-2(R)-[[[2-(2-methyl-1H-benzimidazol-1-yl)ethyl]amino]carbonyl]-4-piperazinecarboxamide 

Relevant academic research and scientific papers

NOVEL INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Novel compounds and pharmaceutical compositions are disclosed which are inhibitors of the enzyme, farnesyl-protein transferase. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering the novel aminooxyamide compound to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammal such as a human.

Inhibitors of farnesyl-protein transferase

Novel compounds and pharmaceutical compositions are disclosed which are inhibitors of the enzyme, farnesyl protein transferase. Also disclosed is a method of inhibiting Ras function and therefore inhibiting the abnormal growth of cells. The method comprises administering the novel aminooxyamide compound to a biological system. In particular, the method inhibits the abnormal growth of cells in a mammals such as a human.