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5-bromo-2-chloro-3H-indol-3-one is a heterocyclic organic compound characterized by the presence of a 3H-indol-3-one core structure, which features a nitrogen atom in a six-membered aromatic ring fused to a five-membered ring containing a carbonyl group. 5-bromo-2-chloro-3H-indol-3-one is specifically substituted with a bromine atom at the 5-position and a chlorine atom at the 2-position. It is a halogenated derivative of the indole family, which is known for its diverse range of biological activities and applications in pharmaceuticals and agrochemicals. The presence of both bromine and chlorine atoms in 5-bromo-2-chloro-3H-indol-3-one may confer unique properties, such as increased lipophilicity or altered reactivity, which could be exploited in various chemical and biological contexts.

6199-96-8

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6199-96-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6199-96-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,1,9 and 9 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 6199-96:
(6*6)+(5*1)+(4*9)+(3*9)+(2*9)+(1*6)=128
128 % 10 = 8
So 6199-96-8 is a valid CAS Registry Number.

6199-96-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-bromo-2-chloroindol-3-one

1.2 Other means of identification

Product number -
Other names 5-BROMO-2-CHLORO-3H-INDOL-3-ONE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6199-96-8 SDS

6199-96-8Upstream product

6199-96-8Relevant academic research and scientific papers

Structure-activity relationships of 2-Aryl-2,5-dihydropyridazino [4,3-b]indol-3(3H)-ones at the benzodiazepine receptor

Palluotto,Carotti,Casini,Campagna,Genchi,Rizzo,De Sarro

, p. 2091 - 2104 (2007/10/03)

A large series of 2-aryl-2,5-dihydropyridazino[4,3-b]indol-3(3H)ones (PIs) carrying properly selected substituents at the indole and N2-phenyl rings was prepared and tested as central benzodiazepine receptor (BZR) ligands and potential (anti)convulsant agents. Stereoelectronic requirements for high receptor affinity were detected by means of 2-D and 3-D QSAR analyses. BZR affinities and pharmacological profiles of the compounds were examined in comparison with some other pyridazinoindolones recently described by us and with pyrazoloquinoline (PQ) analogues. An anticonvulsant activity greater than PQs was generally observed for PIs. Notably, in the test of audiogenically induced seizures, one compound showed a potency comparable to that of diazepam.

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