61996-35-8

Basic information

• Product Name: Acetamide, N-methyl-N-2-pyridinyl-
• Synonyms: Acetamide, N-methyl-N-2-pyridinyl-;ACETAMIDE,N-METHYL-N-PYRIDIN-2-YL-;2-(N-METHYL-N-ACETYL)-AMINOPYRIDINE
• CAS NO: 61996-35-8
• Molecular Formula: C₈H₁₀N₂O
• Molecular Weight: 150.18
• Mol File: 61996-35-8.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Acetamide, N-methyl-N-2-pyridinyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetamide, N-methyl-N-2-pyridinyl-(61996-35-8)
• EPA Substance Registry System: Acetamide, N-methyl-N-2-pyridinyl-(61996-35-8)

Safety Data

• Hazardous Substances Data: 61996-35-8(Hazardous Substances Data)

Upstream product

• 694-59-7 pyridine N-oxide 
• 79-16-3 N-methyl-acetamide 
• 996-25-8 N-methyl-acetimidoyl chloride 
• 5231-96-9 N-(2-pyridyl)acetamide 
• 74-88-4 methyl iodide 
• 4597-87-9 2-(N-methylamino)pyridine 
• 108-24-7 acetic anhydride 

Downstream Products

• 4597-87-9 2-(N-methylamino)pyridine 
• 92053-37-7 thioacetamide N(2-pyridylmethyl) 
• 3187-58-4 methyl orsellinate 

Relevant articles and documents

Recent developments in the chemistry of heteroaromatic N -oxides

Selected developments in the chemistry of heteroaromatic N-oxides since 2001 are presented in this review. The use of these N-oxides, both in late-transition-metal-catalyzed oxidations of carbon-carbon triple bonds and in regioselective C-H functionalizations of the heteroarene, are contemporary topics of interest and the focus of the discussion. 1 Introduction 2 Synthesis of Heteroaromatic N-Oxides 2.1 Direct Oxidation of Hindered Heteroarenes 2.2 Through Construction of Heteroaromatic Rings 3 Heteroaromatic N-Oxides as Oxidants 3.1 Alkyne Oxidation 3.2 Allene Oxidation 3.3 Carbene Oxidation 4 Heteroaromatic N-Oxides as Substrates 4.1 Deoxygenative ortho-C-H Functionalization with Prior Activation 4.2 Deoxygenative ortho-C-H Functionalization with Nonstabilized Carbanions 4.3 Nondeoxygenative C-H Functionalization 4.3.1 ortho-C-H Functionalization 4.3.2 N-Oxide Directed ortho-Alkyl C-H Functionalization 4.3.3 N-Oxide Directed Remote C-H Functionalization 4.4 1,3-Dipolar Cycloaddition 5 Conclusion and Outlook.

Acid-induced conformational alteration of cis-preferential aromatic amides bearing N-methyl-N-(2-pyridyl) moiety

A series of cis-preferential aromatic N-methyl amides was designed and synthesized, and acid-induced conformational alteration of these compounds was investigated by means of NMR measurements in solution and X-ray crystal structure analysis. Compounds with a terminal N-methyl-N-(2-pyridyl) amide unit showed acid-induced conformational change from cis to trans, while those with a terminal N-methyl-2-pyridinecarboxamide unit showed a change of the carbonyl orientation from anti to syn with retention of cis conformation.

A mild method for the formation and in situ reaction of imidoyl chlorides: conversion of pyridine-1-oxides to 2-aminopyridine amides.

[reaction: see text] A mild, practical, one-pot method for the generation of imidoyl chlorides and their subsequent in situ reaction with pyridine-1-oxides is described. The imidoyl chlorides were formed from the reaction of secondary amides with a stoich

Convenient Syntheses of Alkyl β-Resorcylate Derivatives

Syntheses of methyl 2,4-dihydroxy-6-methyl- (1a) and -3,6-dimethylbenzoates (1b) and methyl 2,4-dihydroxy-6-pentylbenzoate (1c) are described.Condensation reactions of dimethyl sodiomalonate with the dianion derived from pentane-2,4-dione or the dimerisation of the methyl acetoacetate dianion or the acetylation of the trianion derived from methyl 3,5,7-trioxo-octanoate gave (1a) (78percent) after work-up at pH 9.Analogous convenient, short, optimised syntheses of (1b and c) are given in detail.