62012-46-8

Upstream product

• 122-78-1 phenylacetaldehyde 
• 1133931-96-0 (1S)-[1-d1]-2-phenylethyl 2,4,6-triisopropylbenzoate 
• 71964-68-6 [1-²H₁]-2-phenylethanal 

Downstream Products

• 1133931-98-2 C₁₈H₁₆⁽²⁾HF₃O₃ 
• 882165-02-8 (3R)-[3-²H₁]-4-phenyl-2-butanone 
• 882165-03-9 (3S)-[3-²H₁]-4-phenyl-2-butanone 
• 882045-81-0 (3R)-[3-²H₁]-4-phenyl-1-butyne 
• 882045-78-5 (1S)-[1-²H₁]-2-phenylethyl tosylate 

Relevant academic research and scientific papers

Method for synthesizing chiral deuterated primary alcohol

The invention discloses a method for synthesizing chiral deuterated primary alcohol. The method comprises the following step: reacting an aldehyde compound in an aprotic organic solvent at room temperature under the action of a chiral cobalt catalyst by t

Enantiopure chiral (2,4,6-triisopropylbenzoyl)oxy-[D1] methyllithium: Configurational stability, reactions, and mechanistic studies

The configurational stability of enantiopure chiral (2,4,6- triisopropylbenzoyl)oxy-[D1]methyllithium generated by a tin-lithium exchange was tested on the macroscopic time scale, employing trapping experiments with benzaldehyde. It was found t

Incorporation of deuterium-labelled analogs of isopentenyl diphosphate for the elucidation of the stereochemistry of rubber biosynthesis

A series of six deuterium-labelled analogs of isopententyl diphosphate (IPP) was prepared to investigate the detailed stereochemical course of addition of C5 units during rubber biosynthesis in Hevea brasiliensis and Parthenium argentatum. These analogs were incorporated into the cis-polyisoprene chain by rubber transferase in rubber particles, and the stereochemistry was determined by 2H-NMR analysis of the polymer or of levulinic acid derivatives obtained from its ozonolytic degradation. Results indicate that rubber chain elongation occurs with loss of the pro-S hydrogen of IPP, addition of the allylic diphosphate to the si face of IPP and inversion of stereochemistry at the carbon bearing the diphosphate. The Royal Society of Chemistry.

On the synthesis of serine and homoserine samples asymmetrically labelled with tritium and deuterium in the hydroxymethylene group

(1R) [1-3H, 2H1] 3-Phenylpropanol, the key intermediate in the synthesis of (4R) [4-3H, 2H1] D,L-homoserine oserine and of the (4S)-isomer, is obtained from (1S) [1-2H1/sub