620179-39-7Relevant academic research and scientific papers
Stereoselective syntheses of tri- and tetrapeptide analogues by dynamic resolution of α-halo amides in nucleophilic substitution
Chang, Ji-Yeon,Shin, Eun-Kyoung,Kim, Hyun Jung,Kim, Yangmee,Park, Yong Sun
, p. 2743 - 2750 (2005)
Dynamic resolution of α-bromo and α-chloro acetamides in nucleophilic substitution with amine nucleophiles in the presence of TBAI has been investigated for stereoselective syntheses of tri- and tetrapeptide analogues. Mechanistic investigations suggest t
Asymmetric nucleophilic substitution of α-bromo amides via dynamic kinetic resolution for the preparation of dipeptide analogues
Nam, Jiyoun,Chang, Ji-Yeon,Shin, Eun-Kyoung,Kim, Hyun Jung,Kim, Yangmee,Jang, Soonmin,Park, Yong Sun
, p. 6311 - 6318 (2007/10/03)
Asymmetric nucleophilic substitution reactions of α-bromo α-aryl acetamides derived from L-amino acids are described. The simple and practical syntheses of dipeptide analogues have been developed with dibenzylamine, TBAI and a base to provide 2a-2n and 4
