62024-29-7Relevant academic research and scientific papers
New aspects of reactions of methyl (thio)ureas with benzil
Baranov, Vladimir V.,Kravchenko, Angelina N.,Nelyubina, Yulia V.,Vol'khina, Tatyana N.
, p. 673 - 676 (2021/11/26)
New pathways of reaction between 1-methylthiourea or 1-methylurea and benzil bring about new derivatives of (2S*,3aR*,6aS*)-perhydro-3aH-[1,3]dioxolo[4,5-d]imidazole and racemic (4S*,5R*)-4-alkoxy-5-hydroxy-1-methyl-4,5-diphenylimidazolidine-2-thiones. So
Structure-activity relationships of 3-substituted-5,5-diphenylhydantoins as potential antiproliferative and antimicrobial agents
Trisovic, Nemanja,Bozic, Bojan,Obradovic, Ana,Stefanovic, Olgica,Markovic, Snezana,Comic, Ljiljana,Bozic, Biljana,Uscumlic, Gordana
scheme or table, p. 1597 - 1606 (2012/05/07)
A series of twelve 3-substituted-5,5-diphenylhydantoins was synthesized, including some whose anticonvulsant activities have already been reported in the literature. Their antiproliferative activities against HCT-116 human colon carcinoma cells were evalu
3-alkyl-(5,5'-diphenyl)imidazolidinediones as new cannabinoid receptor ligands
Kanyonyo, Martial,Govaerts, Sophie J.,Hermans, Emmanuel,Poupaert, Jacques H.,Lambert, Didier M.
, p. 2233 - 2236 (2007/10/03)
Twenty-four 3-alkyl-(5,5'-diphenyl)imidazolidinediones were synthesized and evaluated as new cannabinoid receptor ligands. Three compounds exhibited a Ki value around 100 nM against [3H]-SR 141716A binding obtained from human CB1 transfected CHO cells membranes. The lack of change of affinity in the presence of a non hydrolyzable GTP analogue seems to indicate they are cannabinoid antagonists.
