62029-81-6

Basic information

• Product Name: 2-AMINO-N-PROPYLACETAMIDE
• Synonyms: 2-AMINO-N-PROPYLACETAMIDE;propylcarbamoylmethylazanium
• CAS NO: 62029-81-6
• Molecular Formula: C₅H₁₂N₂O
• Molecular Weight: 116.16
• Mol File: 62029-81-6.mol

Chemical Properties

• Boiling Point: 270.2°Cat760mmHg
• Flash Point: 117.2°C
• Appearance: /
• Density: 0.962g/cm³
• Vapor Pressure: 0.00695mmHg at 25°C
• CAS DataBase Reference: 2-AMINO-N-PROPYLACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-AMINO-N-PROPYLACETAMIDE(62029-81-6)
• EPA Substance Registry System: 2-AMINO-N-PROPYLACETAMIDE(62029-81-6)

Safety Data

• Hazardous Substances Data: 62029-81-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
2-AMINO-N-PROPYLACETAMIDE is used as a precursor in the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new drugs and agricultural products.
Used in Dye Production:
2-AMINO-N-PROPYLACETAMIDE is utilized in the production of dyes, playing a crucial role in the creation of colorants for various applications.
Used in Electroplating Solutions:
It is also employed in the formulation of electroplating solutions, which are essential for the surface finishing and enhancement of various metal components.
Safety Precautions:
When handling 2-AMINO-N-PROPYLACETAMIDE, it is important to exercise caution due to its corrosive properties. Proper safety procedures and the use of protective equipment are necessary to minimize the risk of exposure and potential harmful effects.

InChI:InChI=1/C5H12N2O/c1-2-3-7-5(8)4-6/h2-4,6H2,1H3,(H,7,8)/p+1

Upstream product

• 107-10-8 propylamine 
• 56-40-6 glycine 

Downstream Products

• 25443-72-5 N-(2-oxo-2-(propylamino)ethyl)-2-phenylacetamide 
• 1314039-61-6 C₂₉H₃₀N₄O₂ 

Relevant articles and documents

Protecting-Group-Free Amidation of Amino Acids using Lewis Acid Catalysts

Amidation of unprotected amino acids has been investigated using a variety of ‘classical“ coupling reagents, stoichiometric or catalytic group(IV) metal salts, and boron Lewis acids. The scope of the reaction was explored through the attempted synthesis of amides derived from twenty natural, and several unnatural, amino acids, as well as a wide selection of primary and secondary amines. The study also examines the synthesis of medicinally relevant compounds, and the scalability of this direct amidation approach. Finally, we provide insight into the chemoselectivity observed in these reactions.

Direct amidation of unprotected amino acids using B(OCH2CF3)3

A commercially available borate ester, B(OCH2CF3)3, can be used to achieve protecting-group free direct amidation of α-amino acids with a range of amines in cyclopentyl methyl ether. The method can be applied to the synthesis of medicinally relevant compounds, and can be scaled up to obtain gram quantities of products.