62030-92-6

Basic information

• Product Name: Methanone, [1-(3-chloropropyl)-4-piperidinyl](4-fluorophenyl)-
• CAS NO: 62030-92-6
• Molecular Formula: C15H19ClFNO
• Molecular Weight: 283.773
• Mol File: 62030-92-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Methanone, [1-(3-chloropropyl)-4-piperidinyl](4-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, [1-(3-chloropropyl)-4-piperidinyl](4-fluorophenyl)-(62030-92-6)
• EPA Substance Registry System: Methanone, [1-(3-chloropropyl)-4-piperidinyl](4-fluorophenyl)-(62030-92-6)

Safety Data

• Hazardous Substances Data: 62030-92-6(Hazardous Substances Data)

Upstream product

• 25503-64-4 4-(4-Fluorobenzoyl)-1-(3-hydroxypropyl)piperidine 
• 56346-57-7 (4-fluorophenyl)-piperidin-4-ylmethanone 
• 109-70-6 1.3-chlorobromopropane 

Downstream Products

• 62030-90-4 1-(10-{3-[4-(4-fluoro-benzoyl)-piperidin-1-yl]-propyl}-10H-phenothiazin-2-yl)-ethanone 
• 136481-49-7 6-[3-(4-(4-fluorobenzoyl)-1-piperidyl)propyl]-6H-dibenzo[c,e]-1,2-thiazine 5,5-dioxide 
• 130944-27-3 1-(p-acetamidophenylsulphono)-3-<4-(4-fluorobenzoyl)piperidino>propane 
• 130944-29-5 1,3-bis<4-(4-fluorobenzhydryl)piperidino>propane 
• 130944-25-1 N-(4-{3-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-propylsulfanyl}-phenyl)-acetamide 
• 130944-26-2 {1-[3-(4-Amino-phenylsulfanyl)-propyl]-piperidin-4-yl}-(4-fluoro-phenyl)-methanone 
• 130944-33-1 (4-Fluoro-phenyl)-{1-[3-(2-trifluoromethyl-phenylamino)-propyl]-piperidin-4-yl}-methanone 
• 130944-21-7 {1-[3-(4-Chloro-phenylsulfanyl)-propyl]-piperidin-4-yl}-(4-fluoro-phenyl)-methanone 
• 130944-24-0 (4-Fluoro-phenyl)-[1-(3-p-tolylsulfanyl-propyl)-piperidin-4-yl]-methanone 
• 130944-22-8 1-(phenylmercapto)-3-<4-(4-fluorobenzoyl)piperidino>-propane 
• 130944-16-0 1-<(4-hydroxy-4-phenyl)piperidin-1-yl>-3-<4-(4-fluorobenzoyl)piperidin-1-yl>propane 
• 130943-94-1 (1-{3-[4-(4-Fluoro-benzoyl)-piperidin-1-yl]-propyl}-piperidin-4-yl)-(4-fluoro-phenyl)-methanone 
• 130944-23-9 (4-Fluoro-phenyl)-{1-[3-(4-methoxy-phenylsulfanyl)-propyl]-piperidin-4-yl}-methanone 
• 62030-88-0 (4-fluoro-phenyl)-{1-[3-(2-trifluoromethyl-phenothiazin-10-yl)-propyl]-piperidin-4-yl}-methanone 

Relevant articles and documents

SEROTONIN ANTAGONISTS, THEIR PREPARATION AND MEDICATIONS CONTAINING THEM

This invention relates to compounds of formula: STR1 in which R. sub.1 denotesa 1,2,3,6-tetrahydro-1-pyridyl radical substituted in the 4-position by an optionally substituted phenyl, optionally substituted 3-indolyl or 3-(5-hydroxyindolyl) radical, a 1-piperazinyl radical substituted in the 4-position by an optionally substituted phenyl, 1,2-benzisothiazol-3-yl, 1,2-benzisoxazol-3-yl or 2-pyridyl radical,a piperidino radical substituted in the 4-position by an optionally substituted phenyl, bis(4-fluorophenyl)methylene, 4-fluorobenzoyl, optionally substituted 2-oxo-1-benzimidazolinyl, optionally substituted 3-indolyl or 3-(5-hydroxyindolyl) radical, by two phenyl radicals or a hydroxyl radical and an optionally substituted phenyl radicalR 2 denotes a radical SO. sub.2 R 4 in which R 4 denotes an alkyl or phenyl radical,R 3 denotes a phenyl or naphthyl radical, or else R 2 and R 3 together with the nitrogen atom to which they are attached form a ring,n is equal to 2, 3 or 4, processes for their preparation and medications containing them. The invention relates to treating a disease ameliorated by serotonin.

1,5-Disubstituted-1,2-dihydro-2H-1,4-benzodiazepin-2-ones

1,5-Disubstituted-1,2-dihydro-2H-1,4-benzodiazepin-2-ones of the formula STR1 wherein R is hydrogen or fluoro, R1 is hydrogen, fluoro chloro, bromo or trifluoromethyl, and n is 2 to 4, having anticonvulsant activity and useful as anti-anxiety agents, are disclosed.