62047-97-6

Upstream product

• 87848-77-9 4-(o-methoxy-p-tolyl)-pentanoic acid methyl ester 
• 170235-80-0 methyl 4-(2'-methoxy-4'-methylphenyl)-5-tosyloxypentanoate 
• 164921-74-8 methyl 4-(2'-methoxy-4'-methylphenyl)-5-hydroxy-(2E)-pentanoate 
• 170235-79-7 5-Hydroxy-4-(2-methoxy-4-methyl-phenyl)-pentanoic acid methyl ester 

Downstream Products

• 155608-76-7 Toluene-4-sulfonic acid 4-(2-methoxy-4-methyl-phenyl)-pentyl ester 
• 170235-81-1 1-iodo-4-(2'-methoxy-4'-methylphenyl)pentane 
• 170235-84-4 4-(2'-methoxy-4'-methylphenyl)pentyl acetate 
• 122427-49-0 5-(2-Hydroxy-4-methyl-phenyl)-hexanoic acid 
• 170235-86-6 4-(2'-methoxymethyloxy-4'-methylphenyl)pentyl acetate 
• 170235-89-9 4-(1,5-dimethyl-4-hexenyl)-3-(methoxymethoxy)toluene 
• 170235-88-8 4-(2-Methoxymethoxy-4-methyl-phenyl)-pentanal 
• 170235-85-5 4-(2'-hydroxy-4'-methylphenyl)pentyl acetate 
• 170235-87-7 4-(2'-methoxymethyloxy-4'-methylphenyl)pentanol 
• 170235-99-1 2,5-bis(methoxymethoxy)-4-(1,5-dimethylhex-4-enyl)toluene 
• 170235-98-0 4-(2,5-Bis-methoxymethoxy-4-methyl-phenyl)-pentanal 
• 170235-83-3 methyl-5-(2'-hydroxy-4'-methylphenyl)hexanoate 
• 122427-48-9 4-(2'-methoxy-4'-methylphenyl)hexanenitrile 
• 78964-27-9 (+/-)-curcuhydroquinone 

Relevant academic research and scientific papers

Reaction of methyl 4,5-epoxy-(2E)-pentenoate with arenes. II. Application to the synthesis of(±)-curcudiol, (±)-curcuphenol, (±)-curcuhydroquinone, and(±)-curcuquinone

Four bisabolane sesquiterpenes, (±)-curcudiol (2), (±)-curcuphenol (3), (±)-curcuhydroquinone (5) and (±)-curcuquinone (6), were synthesized based on the reaction of methyl 4,5-epoxy-(2E)-pentenoate (1) with methoxytoluenes in the presence of boron trifluoride etherate.

A FACILE SYNTHESIS OF 4-ARYL-5-HYDROXY-(2E)-PENTENOATE DERIVATIVES AND ITS APPLICATIONS TO THE FIRST SYNTHESIS OF (+/-)-CURUCUDIOL, (+/-)-CURCUHYDROQUINONE AND (+/-)-CURCUQUINONE

The first syntheses of three kinds of bisabolane sesquiterpenes, (+/-)-curcudiol (29), (+/-)-curcuhydroquinone (40) and (+/-)-curcuquinone (41) were achieved based on the BF3*Et2O catalyzed reaction of (+/-) methyl 4,5-epoxy-(2E)-pentenoate (1) and polyme